The role of air pollution in epilepsy: a better understanding is needed.

IF 1.6 4区 医学 Q4 NEUROSCIENCES
Arquivos de neuro-psiquiatria Pub Date : 2025-06-01 Epub Date: 2025-07-02 DOI:10.1055/s-0045-1809663
Prem Jareonsettasin, John S Ji, Xiaowen Zhou, Ding Ding, Josemir W Sander
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引用次数: 0

Abstract

Social determinants of health, including neighborhood and built environment factors, play a crucial but underexplored role in epilepsy incidences. Among these, air pollution emerges as a potentially-preventable driver of epilepsy and adverse health outcomes. Evidence is accumulating on the effects of air pollution on the brain, especially in stroke and neurodegenerative disorders; however, the specific impact on epilepsy remains underresearched, potentially due to the complexities of studying this condition. The present narrative review addresses a critical knowledge gap by exploring: 1) the role of air pollution in epilepsy epidemiology; 2) the biological mechanisms of air pollution in the brain in the context of epilepsy; and 3) how air pollution affects the management of people living with epilepsy. We outline vital questions and actionable interventions regarding the role of air pollution in epilepsy.

空气污染在癫痫中的作用:需要更好地了解。
健康的社会决定因素,包括邻里和建成环境因素,在癫痫发病率中发挥着至关重要但尚未得到充分探索的作用。其中,空气污染成为癫痫和不良健康后果的潜在可预防驱动因素。越来越多的证据表明,空气污染对大脑的影响,特别是对中风和神经退行性疾病的影响;然而,对癫痫的具体影响仍未得到充分研究,这可能是由于研究这种情况的复杂性。目前的叙述性综述通过探索解决了一个关键的知识缺口:1)空气污染在癫痫流行病学中的作用;2)癫痫背景下空气污染对大脑的生物学机制;3)空气污染如何影响癫痫患者的管理。我们概述了有关空气污染在癫痫中的作用的重要问题和可行的干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Arquivos de neuro-psiquiatria
Arquivos de neuro-psiquiatria 医学-精神病学
CiteScore
2.10
自引率
7.10%
发文量
262
审稿时长
4-8 weeks
期刊介绍: Arquivos de Neuro-Psiquiatria is the official journal of the Brazilian Academy of Neurology. The mission of the journal is to provide neurologists, specialists and researchers in Neurology and related fields with open access to original articles (clinical and translational research), editorials, reviews, historical papers, neuroimages and letters about published manuscripts. It also publishes the consensus and guidelines on Neurology, as well as educational and scientific material from the different scientific departments of the Brazilian Academy of Neurology. The ultimate goals of the journal are to contribute to advance knowledge in the areas of Neurology and Neuroscience, and to provide valuable material for training and continuing education for neurologists and other health professionals working in the area. These goals might contribute to improving care for patients with neurological diseases. We aim to be the best Neuroscience journal in Latin America within the peer review system.
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