Barış Timur, Rezan Aksoy, Zihni Mert Duman, Recep Çalışkan, Kandemir Baş, Cem Aydoğdu, Cevdet Ugur Kocogullari
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引用次数: 0
Abstract
This study explores the impact of left ventricular mass and geometry on the prognosis of patients undergoing coronary artery bypass grafting. Left ventricular hypertrophy is a known risk factor for cardiovascular complications, yet its role in surgical outcomes remains underexplored.A retrospective cohort of 494 elective coronary artery bypass grafting patients treated between 2013 and 2018 was analyzed. Left ventricular mass was calculated using the Devereux formula, and patients were divided into normal and increased left ventricular mass index groups. Mortality rates, postoperative complications, and echocardiographic parameters were evaluated.Patients with increased left ventricular mass exhibited significantly higher 5-year mortality rates (27.2 vs. 11.5%, p < 0.001), postoperative atrial fibrillation (24.8 vs. 16.0%, p = 0.018), and carotid stenosis (21.8 vs. 12.5%, p = 0.006). Elevated preoperative biomarkers, including creatinine and C-reactive protein, were observed in this group, with sustained impairment in postoperative kidney function. However, no significant differences in 30-day, 1-year, or 3-year mortality rates were detected.Left ventricular mass and geometry independently predict long-term outcomes in coronary artery bypass grafting patients. Targeted strategies to mitigate left ventricular remodeling may enhance postoperative outcomes. Future research should focus on therapeutic interventions to reverse adverse left ventricular changes and optimize patient survival and quality of life.
本研究探讨左心室体积和几何形状对冠状动脉搭桥术患者预后的影响。左心室肥厚是已知的心血管并发症的危险因素,但其在手术结果中的作用仍未得到充分探讨。对2013年至2018年间接受择期冠状动脉搭桥术治疗的494例患者进行回顾性队列分析。采用Devereux公式计算左室质量,将患者分为左室质量指数正常组和左室质量指数升高组。评估死亡率、术后并发症和超声心动图参数。左心室体积增大患者的5年死亡率(27.2 vs. 11.5%, p p = 0.018)和颈动脉狭窄(21.8 vs. 12.5%, p = 0.006)显著升高。术前生物标志物,包括肌酐和c反应蛋白升高,在该组中观察到,术后肾功能持续受损。然而,在30天、1年和3年死亡率方面没有发现显著差异。左心室质量和几何独立预测冠状动脉旁路移植术患者的长期预后。有针对性的策略减轻左心室重构可能会提高术后疗效。未来的研究应侧重于治疗干预,以逆转不良的左心室改变,优化患者的生存和生活质量。
期刊介绍:
The Thoracic and Cardiovascular Surgeon publishes articles of the highest standard from internationally recognized thoracic and cardiovascular surgeons, cardiologists, anesthesiologists, physiologists, and pathologists. This journal is an essential resource for anyone working in this field.
Original articles, short communications, reviews and important meeting announcements keep you abreast of key clinical advances, as well as providing the theoretical background of cardiovascular and thoracic surgery. Case reports are published in our Open Access companion journal The Thoracic and Cardiovascular Surgeon Reports.