Effect of the implementation of HIV/AIDS prevention and treatment policies on the mortality rate of people living with HIV in Guilin, China.

IF 3.9 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-07-02 DOI:10.1038/s41598-025-07683-2

Yan Feng, Ying Zhuo, Jie Tang, Guodong Zhang, Wuxiang Shi, Lingmi Zhou

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Abstract

To analyze the changing trend of HIV/AIDS-related mortality before and after the implementation of the "Prevention and Treatment of HIV/AIDS" policy in Guilin from 1996 to 2020, and to evaluate its effect on HIV/AIDS prevention and treatment. The data of people with HIV reported in Guilin up to December 31, 2020, were obtained from the Chinese Center for Disease Control and Prevention (CDC), and the two rounds of "Prevention and Treatment of HIV/AIDS" policy intervention boundary points were taken in 2010 and 2015, respectively. The interruption time series (ITS) analysis was used to analyze the trend of HIV/AIDS-related mortality before and after the implementation of the HIV/AIDS Prevention and Treatment Project. From 1996 to 2020, the HIV/AIDS mortality rate decreased in Guilin, and the HIV/AIDS mortality rate of farmers was higher than the overall HIV/AIDS mortality rate. The ITS method analysis results showed that after the implementation of two rounds of "Prevention and Treatment of HIV/AIDS" policy, HIV/AIDS mortality rate showed a downward trend. Between 2010 and 2015, the overall decline in HIV/AIDS mortality rate exhibited a slope of -2.217 (P < 0.01). For individuals with an education level of high school or below, the decline in HIV/AIDS mortality rate during this period had a slope of -2.110 (P < 0.01). Among the farmer population, the decline in HIV/AIDS mortality rate from 2010 to 2015 was even more significant, with a slope of -2.510 (P < 0.01). From 2015 to 2020, the overall HIV/AIDS mortality rate continued to decline, showing a slope of -0.230 (P < 0.01). Between 2015 and 2020, for those with an education level of high school or below, the decline in HIV/AIDS mortality rate had a slope of -0.225 (P < 0.01). In contrast, the decline in HIV/AIDS mortality rate among farmers from 2015 to 2020 was steeper, with a slope of -0.319 (P < 0.01). From 2010 to 2020, the HIV/AIDS mortality rate in Guilin has shown a decreasing trend, indicating that the implementation of the "Prevention and Treatment of HIV/AIDS" policy has achieved good results.

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桂林市艾滋病防治政策实施对艾滋病毒感染者死亡率的影响

分析1996 - 2020年桂林市“防治艾滋病”政策实施前后艾滋病相关死亡率的变化趋势，评价其对艾滋病防治的效果。桂林市截至2020年12月31日报告的HIV感染者数据来源于中国疾病预防控制中心，2010年和2015年分别取两轮“防治HIV/AIDS”政策干预边界点。采用中断时间序列（ITS）分析，分析艾滋病防治项目实施前后艾滋病相关死亡率的变化趋势。1996 - 2020年，桂林市艾滋病死亡率呈下降趋势，农民艾滋病死亡率高于总体艾滋病死亡率。ITS方法分析结果显示，在实施两轮“防治艾滋病”政策后，艾滋病死亡率呈下降趋势。2010年至2015年期间，艾滋病毒/艾滋病死亡率的总体下降斜率为-2.217 (P

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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