Integrating Biosensors in Phytochemical Research: Challenges and Breakthroughs.

Q3 Biochemistry, Genetics and Molecular Biology
Hanuman Ram Choudhary, Dileep Kumar B, Sunil Kumar Kadiri, Deepak S Khobragade, Prashant Tiwari
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引用次数: 0

Abstract

Biosensors are devices that generate signals by interaction of biological elements and analytes, mainly based on their concentration. These are especially composed of enzymes or antibodies. They are associated with a physio-chemical transducer. Their rapid, simple, and real-time detection is of great importance in chemistry, analysis, and drug discovery and development. Phytoconstituents are biologically active compounds mainly synthesized by plants to support their growth and defend against various stresses. Medicinal plants and their products have a vast history of use in traditional medicine, but they are not reliable due to their narrow range and adverse and toxic effects. Moreover, they have vast therapeutic effects on humans, from antibiotics to anti-neoplastic agents. Hence, there is a need for an efficient method to detect and measure these phytoconstituents, and biosensors seem to be the solution. This article provides an overview of various biosensors that can be utilized to identify widely used phytoconstituents, also known as secondary metabolites, such as alkaloids, tannins, flavonoids, terpenoids, cardiac glycosides, and phenolic compounds. The article discusses different types of biosensors, including impedimetric immunosensors, Riboswitch-based biosensors, DNA biosensors, electrochemical biosensors, and others.

整合生物传感器在植物化学研究中的挑战与突破。
生物传感器是通过生物元素和分析物的相互作用产生信号的装置,主要基于它们的浓度。它们特别由酶或抗体组成。它们与一个物理化学传感器相连。它们的快速、简单和实时检测在化学、分析和药物发现和开发中具有重要意义。植物成分是植物合成的具有生物活性的化合物,主要用于支持植物生长和抵御各种胁迫。药用植物及其产品在传统医学中有着悠久的使用历史,但由于它们的范围狭窄和不良和毒性作用,它们并不可靠。此外,它们对人类有巨大的治疗作用,从抗生素到抗肿瘤药物。因此,需要一种有效的方法来检测和测量这些植物成分,而生物传感器似乎是解决方案。本文概述了各种生物传感器可用于识别广泛使用的植物成分,也称为次生代谢物,如生物碱、单宁、黄酮类、萜类、心苷和酚类化合物。本文讨论了不同类型的生物传感器,包括阻抗免疫传感器、基于核糖开关的生物传感器、DNA生物传感器、电化学生物传感器等。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Recent patents on biotechnology
Recent patents on biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
2.90
自引率
0.00%
发文量
51
期刊介绍: Recent Patents on Biotechnology publishes review articles by experts on recent patents on biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.
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