Optical coherence tomography angiography integrating differential phase and intensity images for in vivo imaging of a mouse retina.

IF 3.1 2区 物理与天体物理 Q2 OPTICS
Optics letters Pub Date : 2025-07-01 DOI:10.1364/OL.557676
Fuwang Wu, Xiang He, Yongjian Li, Xiaoqi Lu, Kaixuan Hu, Hongtao Wei, Wei Yi, Yi Wan, Weiye Song
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引用次数: 0

Abstract

Optical coherence tomography angiography (OCTA) suffers from more motion artifacts compared to optical coherence tomography, which are the primary source of image quality degradation in in vivo imaging. We propose an OCTA algorithm in this Letter that differs from motion compensation methods widely employed to reduce motion artifacts and effectively mitigates these artifacts. The algorithm integrates differential phase and intensity images based on the standard deviation of the flow signals. The performance of this algorithm is evaluated on mouse retina in vivo imaging. Compared to three conventional OCTA algorithms, the OCTA images obtained by the proposed algorithm exhibit fewer motion artifacts and less noise in tissue regions, with maximum improvements of 1.38 dB and 0.82 in signal-to-noise ratio and contrast-to-noise ratio (CNR), respectively, in the maximum projection of en face images.

整合不同相位和强度图像的光学相干断层血管造影用于小鼠视网膜的体内成像。
与光学相干断层扫描相比,光学相干断层扫描(OCTA)存在更多的运动伪影,这是体内成像中图像质量下降的主要原因。我们在这封信中提出了一种OCTA算法,它不同于广泛用于减少运动伪影并有效减轻这些伪影的运动补偿方法。该算法基于流量信号的标准差对差分相位和强度图像进行整合。在小鼠视网膜的活体成像上对该算法的性能进行了评价。与三种传统的OCTA算法相比,该算法获得的OCTA图像在组织区域表现出更少的运动伪影和更小的噪声,在人脸图像的最大投影中,信噪比和对比噪声比(CNR)分别提高了1.38 dB和0.82。
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来源期刊
Optics letters
Optics letters 物理-光学
CiteScore
6.60
自引率
8.30%
发文量
2275
审稿时长
1.7 months
期刊介绍: The Optical Society (OSA) publishes high-quality, peer-reviewed articles in its portfolio of journals, which serve the full breadth of the optics and photonics community. Optics Letters offers rapid dissemination of new results in all areas of optics with short, original, peer-reviewed communications. Optics Letters covers the latest research in optical science, including optical measurements, optical components and devices, atmospheric optics, biomedical optics, Fourier optics, integrated optics, optical processing, optoelectronics, lasers, nonlinear optics, optical storage and holography, optical coherence, polarization, quantum electronics, ultrafast optical phenomena, photonic crystals, and fiber optics. Criteria used in determining acceptability of contributions include newsworthiness to a substantial part of the optics community and the effect of rapid publication on the research of others. This journal, published twice each month, is where readers look for the latest discoveries in optics.
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