Effectiveness of therapeutic exercise and platelet-rich plasma in the case of knee osteoarthritis.

Christina Foi, Charalampos Matzaroglou, Georgios Vlachopoulos, Dionysios J Papachristou
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Abstract

[Purpose] Osteoarthritis is the most common form of arthritis worldwide and has detrimental effects on an individual's quality of life. We compared two interventions-an exercise program alone and an exercise program combined with the intra-articular platelet-rich plasma (PRP) injection-focusing on pain and functionality in patients with mild knee osteoarthritis. [Participants and Methods] A total of 76 patients (41 men and 35 women) participated in the study. They were divided equally into the control and intervention groups. To assess knee functionality in both groups, we used state-of-the-art assessment tools, namely the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Knee Injury and Osteoarthritis Outcome Score (KOOS). [Results] The results revealed that following the eight-week exercise program, the intervention group showed significantly better values in the WOMAC scale and in three of the four components of the KOOS scale (pain, symptoms, and activities of daily living). Additionally, we observed that the improvement in WOMAC and KOOS scores was significantly better in the intervention group than in the control group. [Conclusion] Combining PRP and exercise therapy can help improve patients' quality of life. However, PRP preparation protocols and exercise prescriptions must be optimized and tailored to individual patient needs.

治疗性运动和富血小板血浆治疗膝关节骨关节炎的效果。
【目的】骨关节炎是世界上最常见的关节炎,对个体的生活质量有不利影响。我们比较了两种干预措施——单独运动计划和运动计划结合关节内富血小板血浆(PRP)注射——重点关注轻度膝骨关节炎患者的疼痛和功能。【对象与方法】共76例患者(男性41例,女性35例)参与研究。他们被平均分为对照组和干预组。为了评估两组患者的膝关节功能,我们使用了最先进的评估工具,即西安大略和麦克马斯特大学骨关节炎指数(WOMAC)和膝关节损伤和骨关节炎结局评分(oos)。[结果]结果显示,经过八周的运动计划,干预组在WOMAC量表和kos量表四个组成部分中的三个(疼痛、症状和日常生活活动)中表现出明显更好的值。此外,我们观察到干预组在WOMAC和kos评分上的改善明显优于对照组。[结论]PRP与运动疗法相结合可提高患者的生活质量。然而,PRP制备方案和运动处方必须优化和量身定制的个别患者的需要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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137
审稿时长
4-8 weeks
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