Detection and diagnostic process of liver abscess secondary to chemotherapy by mucor indicus in a patient with acute leukemic disease: case report.

Abstract

Mucormycosis is a rare opportunistic fungal infection usually seen in patients with diabetic ketoacidosis or severe immunocompromise. It is difficult to diagnose, progresses rapidly, and has a high morbidity and mortality rate. Clinical adult hepatic mucormycosis is very rare.A 60-year-old male patient was diagnosed with acute leukemia. Lung and liver infections developed during myelosuppression after induction of chemotherapy. Direct microscopic examination and histopathologic examination of the punctured liver tissue revealed mucormycosis fungi. The patient was given antifungal treatment with amphotericin B in combination with posaconazole and liver function improved. We report this clinical case with the intention of improving the clinical detection and diagnosis of hepatic mucormycosis secondary to chemotherapy for leukemia. It also aims to deepen the understanding of this disease and to reduce the occurrence of missed diagnosis and misdiagnosis when encountering hepatic mucormycosis infection in future clinical work.