Analysis of nosocomial infection characteristics in cancer patients after interventional therapy of 10 years: a retrospective study from 2013 to 2022.

Abstract

Background: Interventional therapy has been widely used in cancer patients as its advantages of minimally invasive, precise positioning and quick recovery. Nosocomial infections are the most common complication, but there are few reports about it. This study intends to analyze the characteristics of nosocomial infection patients after interventional therapy of the past 10 years, in order to provide guidances for the infection control.

Methods: The "Hospital Infection Real-time Monitoring System" was used to retrieve case information of patients undergoing intervention therapy from 2013 to 2022, and the general situation of the patients and infected patients was recorded in detail. Statistical software was used to analyze relevant indicators.

Results: From 2013 to 2022, a total of 12,343 hospitalized patients had 190 hospital infections, with an infection rate of 1.54%. The lowest hospital infection rate was 0.62% in 2022 and the highest was 2.76% in 2017, with a statistically significant difference (χ2 = 40.713, P = 0.000); Over the past 10 years, infection site in the bloodstream ranked first (46.98%), followed by surgical site infection (21.40%). Gram positive bacteria (50.75%) was the mainly pathogenic bacteria, followed by Gram negative bacteria (42.29%). Analysis of infection status shows that patients over 60 years old, undergone multiple (≥6) interventional surgeries, biliary tract pancreatic disease, liver cancer, and those who had undergone PTCD and TACE surgery have a higher infection rate.

Conclusions: The analysis of infection occurrence in patients of interventional therapy in 10 years can reflect the risk factors and high-risk links, which can help to take targeted control measures.