Infection prevention and control measures for emerging infectious disease: lessons learned from the first case of imported Lassa fever in China.

IF 4.4 2区医学 Q1 INFECTIOUS DISEASES

Antimicrobial Resistance and Infection Control Pub Date : 2025-07-01 DOI:10.1186/s13756-025-01597-4

Yalan Peng, Yantong Wang, Shiyu Li, Jing Huang, Wu Shi, Ruocheng Luo, Xianmou Pan, Wenzhi Huang, Fu Qiao, Yi Chen

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引用次数: 0

Abstract

Background: Lassa fever is an acute viral hemorrhagic disease prevalent in West Africa. West China Hospital of Sichuan University (WCHSCU) received China's first imported case of Lassa fever from overseas. We described the epidemiological investigation and infection prevention and control measures of this case following the confirmed diagnosis.

Methods: An emergency epidemiological team defined close contacts and implemented infection prevention and control (IPC) measures: (1) isolation in a designated isolation room, (2) environmental disinfection for high-, medium-, and low-risk areas, (3) 21-day quarantine for contacts. Data were collected via field observations and medical records.

Results: We identified 6 close contacts and 74 general contacts, who were subsequently quarantined for 21 days. The hospital environment was classified into high, medium, and low-risk areas, and corresponding cleaning and disinfection measures were implemented. Ultimately, no new infection cases emerged.

Conclusion: Rapid risk stratification, strict isolation protocols, and multidisciplinary coordination effectively prevented transmission, underscoring the importance of preparedness in non-endemic regions.

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新发传染病感染防控措施：中国首例输入性拉沙热的经验教训

背景：拉沙热是西非流行的一种急性病毒性出血性疾病。四川大学华西医院收治中国首例境外输入性拉沙热病例。我们描述了确诊后的流行病学调查和感染防控措施。方法：由流行病学应急小组确定密切接触者并实施感染防控措施：(1)指定隔离室隔离；(2)高、中、低风险区域环境消毒；(3)接触者隔离21天。通过实地观察和医疗记录收集数据。结果：发现密切接触者6人，一般接触者74人，隔离21天。将医院环境分为高、中、低风险区，并实施相应的清洁消毒措施。最终，没有出现新的感染病例。结论：快速的风险分层、严格的隔离方案和多学科协调有效地预防了传播，强调了在非流行地区做好准备的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Antimicrobial Resistance and Infection Control PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

9.70

自引率

3.60%

发文量

140

审稿时长

13 weeks

期刊介绍： Antimicrobial Resistance and Infection Control is a global forum for all those working on the prevention, diagnostic and treatment of health-care associated infections and antimicrobial resistance development in all health-care settings. The journal covers a broad spectrum of preeminent practices and best available data to the top interventional and translational research, and innovative developments in the field of infection control.