Three Years Outcome Comparison of Remote Monitoring Versus Conventional Automated Peritoneal Dialysis in Incident APD Patients: A Retrospective Study From Taiwan.

Mu-Chi Chung, Tung-Min Yu, Laing-You Wu, Ching-Ching Hsiao, Ya-Wen Chuang, Ming-Ju Wu, Cheng-Hsu Chen, Chi-Jung Chung
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Abstract

Aim: The efficacy of the remote monitoring of automated peritoneal dialysis (RM-APD) with Sharesource platform versus conventional APD outcomes in East Asia remains limited.

Methods: This study analysed data from incident APD patients at Taichung Veterans General Hospital between 2010 and 2021. Patients were categorised into RM-APD (n = 77, initiated March 2019-Dec 2021) and conventional APD groups (n = 100, initiated Jan 2010-Dec 2017). Follow-up for both groups extended to censoring, studied outcomes, or the end of the observation period (Dec 2018 for conventional APD and Dec 2022 for RM-APD), with a maximum follow-up of 3 years. Outcomes included death, technique survival, peritonitis incidence and hospitalisation rates using Cox proportional hazard models.

Results: Among 452 patients undergoing peritoneal dialysis, 177 were included after exclusions. Mean age was 49 years in RM-APD and 46 years in conventional APD groups. After mean follow-up of 2.05 years, no significant differences were found in mortality, technique survival rates, or hospitalisation rates between groups. However, RM-APD showed significantly lower peritonitis incidence compared to conventional APD (HR = 0.39, 95% CI: 0.17-0.90, p < 0.05). The conventional APD group had 3 relapse peritonitis and 2 transfer to HD, while the RM-APD group had none.

Conclusions: RM-APD using Sharesource platform significantly reduces peritonitis incidence compared to conventional APD in Taiwan. While mortality and technique survival were similar, improved peritonitis outcomes suggest RM-APD can enhance care quality and safety for incident APD patients in clinical practice. Further prospective studies are warranted to validate these findings.

远程监测与传统自动腹膜透析治疗APD的三年疗效比较:来自台湾的回顾性研究。
目的:在东亚地区,Sharesource平台远程监测自动腹膜透析(RM-APD)与传统APD结果的疗效仍然有限。方法:本研究分析2010年至2021年台中退伍军人总医院APD事件患者的数据。患者被分为RM-APD组(n = 77,于2019年3月至2021年12月开始治疗)和常规APD组(n = 100,于2010年1月至2017年12月开始治疗)。两组的随访时间均延长至审查、研究结果或观察期结束(常规APD为2018年12月,RM-APD为2022年12月),最长随访时间为3年。结果包括使用Cox比例风险模型的死亡、技术生存、腹膜炎发生率和住院率。结果:452例腹膜透析患者中,排除后纳入177例。RM-APD组平均年龄49岁,常规APD组平均年龄46岁。平均随访2.05年后,两组之间的死亡率、技术生存率或住院率均无显著差异。然而,与传统APD相比,RM-APD的腹膜炎发生率显著降低(HR = 0.39, 95% CI: 0.17-0.90, p)。结论:台湾地区使用Sharesource平台的RM-APD与传统APD相比,腹膜炎发生率显著降低。虽然死亡率和技术生存率相似,但改善腹膜炎结局表明RM-APD可以提高临床实践中偶发APD患者的护理质量和安全性。需要进一步的前瞻性研究来验证这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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