Combined hereditary spherocytosis and β-thalassaemia trait: A rare co-existence.

Abstract

Haemoglobinopathies, the most prevalent haemolytic disease in India, make up the majority of patients in most haematology outpatient clinics. The most prevalent hereditary haemolytic anaemia is beta-thalassaemia trait (βTT). It often remains undiagnosed as it has an asymptomatic clinical course. However, βTT needs be identified to provide genetic counselling to the affected families and to reduce the number of affected children born, which will lower their overall financial burden. Better screening methods for haemoglobinopathies have increased the detection of mixed haemolytic anaemia. We report a patient with combined βTT and hereditary spherocytosis.