[Research advances on the mechanism and clinical application of cold atmospheric plasma in promoting wound healing].

Abstract

Wound healing is a complex biological process involving multiple stages, including hemostasis, inflammation, proliferation, and remodeling. Cold atmospheric plasma (CAP), as an efficient, non-invasive, and innovative therapy for wound care, has significant application prospects in this field. It has been demonstrated that CAP can promote wound cell proliferation and reduce microbial load on wounds through various mechanisms. Through a comprehensive analysis of recent domestic and international literature on the biological effects of CAP, this paper reviews how CAP promotes the repair of acute and chronic wounds from the perspectives of mechanism and clinical application and the research progress in the application methods of CAP in recent years.