Status of Body Mass Index and Blood Pressure in Low Dose Oral Contraceptive Pill Users.

Mymensingh medical journal : MMJ Pub Date : 2025-07-01
A Begum, A Nessa, U H Khanom, I Mansoora, F S Joarder
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Abstract

Low dose oral contraceptives are a major category of prescription drugs used by a large number of reproductive women. Since the introduction of the first combined oral contraceptives in the 1960s, great progress has been made to reduce side effects and improve tolerability without compromising efficacy. The most commonly used are combinations of drugs that contain both estrogen and progesterone. Long-term use of hormonal contraceptives by women of reproductive age can lead to increase body mass index (BMI) and blood pressure. The aim of this study was to estimate the status of body mass index and blood pressure in low dose oral contraceptive pill users in Mymensingh locality. This cross sectional analytical type of study was conducted in the Department of Physiology, Mymensingh Medical College, Bangladesh from July 2023 to June 2024. A total number of 140 reproductive women, age ranged from 18-52 years was included in this study. Among them 70 low dose oral contraceptive pill non users were taken as control group (Group I) and 70 low dose oral contraceptive pill users were taken as study group (Group II). The results were calculated and analyzed by using SPSS (Statistical Product and Service Solutions), version 26.0. Data were expressed in Mean ±SD and statistical significance of difference among the groups was calculated by unpaired Student's 't' test. Correlation among body mass index, systolic blood pressure and diastolic blood pressure were done by Pearson's correlation coefficient test. The mean±SD of body mass index (BMI) of control group and study group were 23.24±2.19 in kg/m2 and 26.60±1.94 in kg/m2 respectively. In study group, body mass index was increased in comparison with control group. The mean ±SD of systolic blood pressure of control group and study group were 122.93±10.88 mm of Hg and 141.66±5.47 mm of Hg respectively. In study group, systolic blood pressure was increased in comparison with control group. The mean ±SD of diastolic blood pressure of control group and study group were 81.21±5.92 mm of Hg and 91.87±6.13 mm of Hg respectively. In study group, diastolic blood pressure was increased in comparison with control group. In this study, body mass index and blood pressure was statistically highly significant (p<0.001) in study group in comparison to control group. Therefore, by this study we recommended that OCP users should follow up for early detection and prevention of complication leading to a healthy life.

低剂量口服避孕药使用者体重指数和血压状况。
低剂量口服避孕药是大量育龄妇女使用的一大类处方药。自20世纪60年代首次采用复方口服避孕药以来,在不影响疗效的情况下,在减少副作用和提高耐受性方面取得了巨大进展。最常用的是含有雌激素和黄体酮的药物组合。育龄妇女长期使用激素避孕药会导致体重指数(BMI)和血压升高。本研究的目的是估计Mymensingh地区低剂量口服避孕药使用者的体重指数和血压状况。这项横断面分析型研究于2023年7月至2024年6月在孟加拉国Mymensingh医学院生理学系进行。本研究共纳入140名育龄妇女,年龄在18-52岁之间。其中70例低剂量口服避孕药非服用者作为对照组(第一组),70例低剂量口服避孕药服用者作为研究组(第二组)。使用SPSS (Statistical Product and Service Solutions) 26.0版本对结果进行计算和分析。数据以Mean±SD表示,组间差异的统计学意义采用unpaired Student’st检验。体质指数与收缩压、舒张压的相关性采用Pearson相关系数检验。对照组和研究组体重指数(BMI)的平均值±SD分别为23.24±2.19 kg/m2和26.60±1.94 kg/m2。研究组体重指数较对照组明显增高。对照组和研究组收缩压均值±SD分别为122.93±10.88 mm Hg和141.66±5.47 mm Hg。研究组患者收缩压较对照组升高。对照组和研究组舒张压均值±SD分别为81.21±5.92 mm Hg和91.87±6.13 mm Hg。研究组患者舒张压较对照组升高。在本研究中,体重指数和血压在统计学上具有高度显著性(p
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