Incidence rate analysis of cutaneous soft tissue sarcomas in the USA.

Abstract

Soft tissue sarcomas (STS) are rare and heterogeneous, with cutaneous STS (CSTS) lacking recent epidemiological data. This study analyses CSTS incidence from 2000 to 2019 using SEER data, identifying 18 181 cases. CSTS was more common in men and non-Hispanic Whites, with Kaposi sarcoma (KS) and dermatofibrosarcoma protuberans (DFSP) being predominant. The overall CSTS incidence was 11.2 per 1 000 000 person-years, with KS having the highest rate. The study reveals a 1.4% annual decline in CSTS rates and highlights ethnic disparities, especially in KS incidence among Non-Hispanic Black patients.