Real world outcomes of Kahook Dual Blade goniotomy in black and Afro-Latinx adult patients with glaucoma: a 2-year retrospective study.

Frontiers in ophthalmology Pub Date : 2025-06-16 eCollection Date: 2025-01-01 DOI:10.3389/fopht.2025.1573937
Ayobami Adebayo, Chester Ng, Daniel Laroche
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Abstract

Background: The Kahook Dual Blade goniotomy has been shown to be efficacious in the treatment of open angle glaucoma. We previously reported 6 months results using the Kahook Dual Blade in Black and Afro-Latino patients.

Objectives: The purpose of this study was to determine the effectiveness and safety of Kahook Dual Blade (KDB) goniotomy alone or coupled with phacoemulsification cataract surgery to minimize intraocular pressure, number of medications used and visual field preservation in Black patients or Afro-Latinx who have open-angle glaucoma (OAG).

Design: This was a retrospective, nonrandomized study that was carried out at two private practices in Harlem, NY and Queens, NY.

Methods: This study consisted of patients with OAG who underwent phacoemulsification combined with goniotomy (PE + KDB) or goniotomy alone (KDB). The Kahook dual blade was used to perform goniotomy in all patients. Reduction of intraocular pressure (IOP) and alleviating the burden of medications were both considered indications for glaucoma surgery. Our research included information on IOP before and after surgery, the number of medications to decrease IOP pressure, visual field mean deviation, during a follow-up period of two years.

Results: At two years we identified 31 patients who had surgery. The preoperative IOP of all 31 eyes which had surgery was 16.7 mmHg which decreased to 14.0 mmHg after two years. The baseline number of topical IOP-lowering medications was 2.4 ± 1.4 at baseline which decreased to 1.6 ± 1.4 (P = 0.02) after two years. The average visual field mean deviation was stable in both groups after two years. Postoperative adverse events were mild and included transient hyphema, IOP spikes, posterior capsule opacification, tearing, glare and mild pain.

Conclusion: In Black or Afro-Latinx patients with open-angle glaucoma, phacoemulsification coupled with Kahook dual-blade goniotomy considerably reduces IOP and the number of medications.

Kahook双刀切开术治疗黑人和非裔拉丁裔青光眼成年患者的实际疗效:一项为期2年的回顾性研究。
背景:Kahook双刀角骨切开术是治疗开角型青光眼的有效方法。我们之前报道了在黑人和非裔拉丁美洲患者中使用Kahook双刀片6个月的结果。目的:本研究的目的是确定Kahook双刀(KDB)巩膜切开或联合白内障超声乳化手术的有效性和安全性,以减少黑人或非洲裔拉丁人开角型青光眼(OAG)患者的眼压、用药数量和视野保护。设计:这是一项回顾性的、非随机的研究,在纽约哈莱姆区和皇后区的两家私人诊所进行。方法:本研究包括超声乳化术联合阴道切开术(PE + KDB)或单纯阴道切开术(KDB)的OAG患者。所有患者均采用Kahook双刀进行阴道切开术。降低眼压和减轻药物负担都被认为是青光眼手术的指征。我们的研究包括手术前后的IOP信息,降低IOP压的药物数量,视野平均偏差,在两年的随访期间。结果:两年后,我们确定了31例患者进行了手术。术前31只眼的IOP为16.7 mmHg,术后2年下降至14.0 mmHg。基线时口服降眼压药物的数量为2.4±1.4个,2年后降为1.6±1.4个(P = 0.02)。两组的平均视野平均偏差在两年后稳定。术后不良事件轻微,包括短暂性前房积血、IOP尖峰、后囊混浊、撕裂、眩光和轻度疼痛。结论:对于开角型青光眼患者,超声乳化术联合Kahook双刀切开术可显著降低IOP和药物用量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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