Iatrogenic posterior retinal break from intravitreal anti-VEGF injection in a vitrectomized eye.

Q3 Medicine

Retinal Cases and Brief Reports Pub Date : 2025-06-20 DOI:10.1097/ICB.0000000000001780

Wesley A Han, Sean D Adrean

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引用次数: 0

Abstract

Purpose: To describe a case of a perforating fluid stream of aflibercept resulting in an iatrogenic retinal break with possible subretinal infiltration using a pre-filled syringe (PFS).

Methods: History, examination, fundus photography, and SD-OCTs.

Results: A 60-year-old female with diabetic macular edema (DME) OU was treated with intravitreal aflibercept (IVA) injections with a PFS. She developed a macular hole (MH), which was repaired with vitrectomy surgery. She required ongoing IVA injections after her MH surgery. Two days following an injection, the patient returned complaining of flashes, floaters, and a red linear streak in her vision. Visual acuity (VA) declined from 20/150 OS to 20/250. Examination showed an iatrogenic posterior retinal break with hemorrhage and edema. Fundus photography, fluorescein angiography and OCT imaging were obtained. After two weeks of observation, the defect had closed. After five weeks, VA returned to 20/150 OS. She resumed IVA injections using PFS.

Conclusions: This case presents a potential complication in vitrectomized patients receiving intravitreal injections.

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玻璃体切除眼玻璃体内注射抗vegf致医源性后视网膜破裂。

目的：描述一个使用预填充注射器（PFS）的阿非利西普穿孔液体流导致可能的视网膜下浸润的医疗源性视网膜破裂的病例。方法：病史、检查、眼底摄影、sd - oct。结果：对1例60岁女性糖尿病性黄斑水肿（DME）患者行玻璃体内注射阿布利塞普（IVA）联合PFS治疗。她出现了黄斑裂孔（MH），并通过玻璃体切除手术修复。她在MH手术后需要持续的IVA注射。注射两天后，患者返回，主诉出现闪光、飞蚊和视觉上的红色线状条纹。视力（VA）由20/150 OS降至20/250 OS。检查显示医源性后视网膜破裂伴出血及水肿。眼底摄影、荧光素血管造影及OCT成像。经过两周的观察，这个缺陷已经愈合了。五周后，VA恢复到20/150 OS。她继续使用PFS进行IVA注射。结论：本病例为玻璃体切除术患者接受玻璃体内注射的潜在并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retinal Cases and Brief Reports Medicine-Ophthalmology

CiteScore

2.10

自引率

0.00%

发文量

342