Drug Ropivacaine in Bilateral Transversus Abdominis Plane (TAP) Block Versus Intramuscular Diclofenac Injection for Post-Caesarean Analgesia: Comparing New Method with Traditional One.
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引用次数: 0
Abstract
Background: Analgesia is an important aspect in post-operative period. Nowadays, various multimodal approaches are used for pain management in surgical patients. With these numerous options, the best choice in setting after LSCS remains debatable. In this study, safety and efficacy of regional blocks like TAP block with ropivacaine for pain control were analysed. This may emerge as a better option for pain control after LSCS with minimal adverse effects to both breastfeeding neonate and mother.
Materials and methods: 250 patients undergoing LSCS (emergency and elective) were prospectively randomized into two groups. One group received intramuscular diclofenac injections thrice daily while another received bilateral TAP block with 20 ml 0.75% ropivacaine. Visual analogue scale (VAS) score, dosage interval, duration of analgesia and rescue dosage requirement between two groups were recorded and analysed.
Results: The mean of total VAS score in group receiving TAP block was lower compared to group receiving IM diclofenac sodium (4.08 ± 3.01 Vs. 14.46 ± 3.98). Also TAP block provided longer duration of analgesia (1227.240 ± 408.118 min vs. 212.120 ± 81.506 min) in single administration. More patients of first group required rescue analgesia within 12 h. Seven patients of diclofenac group required stopping and shifting to alternate analgesic due to inadequate uterine contractions and required uterotonics administration.
Conclusion: 0.75% ropivacaine in TAP block was effective and had better analgesic and safety profile with comparable cost to IM diclofenac and hence should be recommended in this setting.
背景:术后镇痛是术后治疗的一个重要方面。目前,各种多模式方法被用于外科患者的疼痛管理。有了这么多的选择,LSCS后的最佳选择仍然存在争议。本研究分析了局部阻滞如TAP阻滞联合罗哌卡因用于疼痛控制的安全性和有效性。这可能是LSCS后疼痛控制的更好选择,对母乳喂养的新生儿和母亲的不良影响最小。材料和方法:250例接受LSCS(急诊和择期)的患者前瞻性随机分为两组。一组每日肌注双氯芬酸3次,另一组双侧用0.75%罗哌卡因阻断TAP 20 ml。记录并分析两组患者视觉模拟评分(VAS)、给药间隔、镇痛持续时间及抢救所需给药剂量。结果:TAP阻断组VAS总评分均值低于IM双氯芬酸钠组(4.08±3.01∶14.46±3.98)。TAP阻滞单次给药的镇痛时间也更长(1227.240±408.118 min vs 212.120±81.506 min)。第一组患者在12 h内需抢救性镇痛较多,双氯芬酸组7例患者因子宫收缩不足需停药换药,需给予子宫强张剂。结论:0.75%罗哌卡因在TAP阻滞中是有效的,具有更好的镇痛和安全性,成本与IM双氯芬酸相当,因此应该推荐在这种情况下使用。
期刊介绍:
Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: · Original Article· Case Report · Instrumentation and Techniques · Short Commentary · Correspondence (Letter to the Editor) · Pictorial Essay