Prognostic significance of nutritional and inflammatory markers in colorectal cancer.

IF 3.2 Q3 ONCOLOGY

World journal of clinical oncology Pub Date : 2025-06-24 DOI:10.5306/wjco.v16.i6.104958

Jon Andreescu, Abrahams Ocanto, Felipe Couñago

引用次数: 0

Abstract

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related mortality worldwide, responsible for approximately 900000 deaths annually. Inflammation and malnutrition significantly influence patients' responses to treatment. Markers such as serum albumin concentration, the prognostic nutritional index, nutritional risk index (NRI), geriatric NRI, and the systemic immune-inflammation index enable the early identification of high-risk patients, facilitating timely interventions that can improve survival and reduce morbidity. A comprehensive understanding and application of these markers allow for better risk stratification in CRC patients, optimizing their management and outcomes.

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营养和炎症标志物在结直肠癌中的预后意义。

结直肠癌（CRC）是第三大最常见的恶性肿瘤，也是全球癌症相关死亡的第二大原因，每年造成约90万人死亡。炎症和营养不良显著影响患者对治疗的反应。血清白蛋白浓度、预后营养指数、营养风险指数（NRI）、老年NRI、全身性免疫炎症指数等指标可以早期发现高危患者，及时干预，提高生存率，降低发病率。全面了解和应用这些标志物可以更好地对结直肠癌患者进行风险分层，优化其管理和预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World journal of clinical oncology ONCOLOGY-

自引率

0.00%

发文量

585

期刊介绍： The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.