Latissimus Dorsi Flap for Chemotherapy-induced Extensive Forearm Necrosis: Case Study.

IF 1.5 Q3 SURGERY

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-06-27 eCollection Date: 2025-06-01 DOI:10.1097/GOX.0000000000006841

Wentao Liu, Menglin Lu, Dan Li, Xiao Shen

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引用次数: 0

Abstract

Chemotherapeutic drug extravasation represents one of the most prevalent complications encountered during chemotherapy administration in oncology patients. A severe consequence of this complication is the induction of extensive soft-tissue necrosis, for which a definitive clinical management protocol remains elusive. This study presented and analyzed a case of an older male patient who developed extensive soft-tissue necrosis in the forearm due to chemotherapeutic drug extravasation, prompting his admission to our department for treatment. The patient underwent repeated debridement procedures, followed by the application of a latissimus dorsi myocutaneous flap combined with skin grafting to cover the wound surface. A 2-month postoperative follow-up revealed satisfactory growth of both the flap and skin graft. This flap transfer technique offers a novel therapeutic approach for the management of extensive soft-tissue necrosis resulting from chemotherapeutic drug extravasation.

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背阔肌皮瓣治疗化疗引起的前臂广泛坏死：个案研究。

化疗药物外渗是肿瘤患者化疗过程中最常见的并发症之一。这种并发症的一个严重后果是引起广泛的软组织坏死，对此尚无明确的临床处理方案。本研究报告并分析了一例老年男性患者，由于化疗药物外渗导致前臂广泛软组织坏死，促使他来我科治疗。患者接受多次清创手术，随后应用背阔肌肌皮瓣联合植皮覆盖创面。术后2个月的随访显示皮瓣和植皮的生长都令人满意。这种皮瓣转移技术为治疗化疗药物外溢引起的广泛软组织坏死提供了一种新的治疗方法。

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来源期刊

Plastic and Reconstructive Surgery Global Open SURGERY-

CiteScore

2.20

自引率

13.30%

发文量

1584

审稿时长

10 weeks

期刊介绍： Plastic and Reconstructive Surgery—Global Open is an open access, peer reviewed, international journal focusing on global plastic and reconstructive surgery.Plastic and Reconstructive Surgery—Global Open publishes on all areas of plastic and reconstructive surgery, including basic science/experimental studies pertinent to the field and also clinical articles on such topics as: breast reconstruction, head and neck surgery, pediatric and craniofacial surgery, hand and microsurgery, wound healing, and cosmetic and aesthetic surgery. Clinical studies, experimental articles, ideas and innovations, and techniques and case reports are all welcome article types. Manuscript submission is open to all surgeons, researchers, and other health care providers world-wide who wish to communicate their research results on topics related to plastic and reconstructive surgery. Furthermore, Plastic and Reconstructive Surgery—Global Open, a complimentary journal to Plastic and Reconstructive Surgery, provides an open access venue for the publication of those research studies sponsored by private and public funding agencies that require open access publication of study results. Its mission is to disseminate high quality, peer reviewed research in plastic and reconstructive surgery to the widest possible global audience, through an open access platform. As an open access journal, Plastic and Reconstructive Surgery—Global Open offers its content for free to any viewer. Authors of articles retain their copyright to the materials published. Additionally, Plastic and Reconstructive Surgery—Global Open provides rapid review and publication of accepted papers.