Risk factors for lower extremity deep vein thrombosis after intertrochanteric fracture of the femur and its response.

IF 1.3 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Feng-Li Wen, Yu-Chen Xiao, Ayidan Ailihemaiti, Jiangannuer Zheyiken
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Abstract

The aim was to investigate the independent risk factors affecting the formation of lower extremity deep vein thrombosis (DVT) after intertrochanteric fracture of the femur, and to propose corresponding preventive measures. Data were collected from patients who underwent intertrochanteric femur fracture surgery in our hospital during the period from January 2020 to December 2023, and the independent risk factors for the formation of postoperative lower limb DVT were determined by univariate and multivariate logistic regression analyses, which led to the construction of the corresponding Nomogram model. The performance of the model was assessed by plotting the subjects' work characteristic curve and its corresponding area under the curve, as well as calibration curve and decision curve analysis. A total of 627 patients with intertrochanteric femoral fractures were included in the study, of whom 156 had postoperative thrombosis, with an incidence rate of 24.88%. By univariate and multivariate logistic regression analyses, 5 independent risk factors associated with lower extremity DVT formation after intertrochanteric femur fracture were identified, including age >75 years (OR: 1.719; 95% CI: 1.094-4.105), body mass index >24 (OR: 2.190; 95% CI: 1.610-2.899), history of preoperative diabetes mellitus (OR: 1.511; 95% CI: 1.079-2.115), high-energy injury (OR: 4.184; 95% CI: 1.977-8.858), and fracture-to-operation time of more than 48 hours (OR: 2.666; 95% CI: 1.964-4.342). The Nomogram model constructed in this study for DVT formation in the lower limb after femoral intertrochanteric fracture showed high predictive accuracy, which can help orthopedic surgeons to identify high-risk patients and intervene early to reduce the occurrence of postoperative DVT.

股骨粗隆间骨折后下肢深静脉血栓形成的危险因素及其反应。
目的探讨影响股骨粗隆间骨折后下肢深静脉血栓形成的独立危险因素,并提出相应的预防措施。收集我院2020年1月至2023年12月行股骨粗隆间骨折手术的患者资料,通过单因素和多因素logistic回归分析确定术后下肢DVT形成的独立危险因素,构建相应的Nomogram模型。通过绘制被试的工作特征曲线及其对应的曲线下面积,以及校正曲线和决策曲线分析来评估模型的性能。共纳入627例股骨粗隆间骨折患者,其中156例发生术后血栓形成,发生率为24.88%。通过单因素和多因素logistic回归分析,确定了与股骨粗隆间骨折后下肢DVT形成相关的5个独立危险因素,包括年龄bb0 ~ 75岁(OR: 1.719;95% CI: 1.094-4.105),体重指数bbb24 (OR: 2.190;95% CI: 1.610-2.899),术前糖尿病史(OR: 1.511;95% CI: 1.079-2.115),高能损伤(OR: 4.184;95% CI: 1.977-8.858),骨折至手术时间大于48小时(OR: 2.666;95% ci: 1.964-4.342)。本研究构建的股骨粗隆间骨折后下肢DVT形成的Nomogram模型具有较高的预测准确率,可帮助骨科医生识别高危患者,早期干预,减少术后DVT的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicine
Medicine 医学-医学:内科
CiteScore
2.80
自引率
0.00%
发文量
4342
审稿时长
>12 weeks
期刊介绍: Medicine is now a fully open access journal, providing authors with a distinctive new service offering continuous publication of original research across a broad spectrum of medical scientific disciplines and sub-specialties. As an open access title, Medicine will continue to provide authors with an established, trusted platform for the publication of their work. To ensure the ongoing quality of Medicine’s content, the peer-review process will only accept content that is scientifically, technically and ethically sound, and in compliance with standard reporting guidelines.
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