Effect of localized cryotherapy on interdigital pruritus of dogs with canine atopic dermatitis.

IF 1.5 3区 农林科学 Q2 VETERINARY SCIENCES
Jae-Il Han, Dongkuk Yoo, Eunjoo Kim, Eun-Soo Lee, Yoonseok Jang, Aryung Nam, Jae-Eun Hyun
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引用次数: 0

Abstract

Importance: Interdigital dermatitis represents a significant clinical manifestation in dogs with atopic dermatitis. Given the refractory nature of these lesions to conventional therapies, there is an increasing demand for novel treatment modalities for atopic interdigital dermatitis.

Objective: This study aimed to evaluate the efficacy and safety of a novel focal cryotherapy device in improving lesions and clinical symptoms in dogs with atopic interdigital dermatitis.

Methods: Twenty dogs diagnosed with atopic interdigital dermatitis were enrolled in this study. Cryotherapy was applied at -5°C for 10 sec to the interdigital spaces. The treatment protocol consisted of three sessions, with 9 dogs receiving weekly treatments and 11 dogs receiving treatments twice weekly. At each visit, a modified Canine Atopic Dermatitis Extent and Severity Index (m-CADESI) and a modified Pruritus Visual Analog Scale (m-PVAS) were employed. Moreover, owner satisfaction and potential adverse effects were evaluated.

Results: Both treatment groups showed improvement in erythema and m-CADESI scores post-treatment. However, a statistically significant reduction in m-PVAS was only observed in treatment group 2. Remarkably, patients with baseline m-CADESI scores ≤ 12 showed significantly greater improvement in m-PVAS compared to those with scores > 12. No significant adverse effects were observed in any of the patients, and owner satisfaction was reported as good to excellent.

Conclusions and relevance: Focal cryotherapy for atopic interdigital dermatitis, when properly indicated, may be considered a novel, safe, and effective treatment option for reducing lesions and pruritus in affected dogs.

局部冷冻治疗犬特应性皮炎指间瘙痒的疗效。
重要性:指间皮炎是犬特应性皮炎的重要临床表现。鉴于这些病变对传统疗法的难治性,对特应性指间皮炎的新型治疗方式的需求日益增加。目的:本研究旨在评估一种新型局灶冷冻治疗装置在改善特应性指间皮炎犬的病变和临床症状方面的有效性和安全性。方法:20只诊断为特应性指间皮炎的狗被纳入本研究。在-5°C下对指间间隙进行冷冻治疗10秒。治疗方案包括三个阶段,9只狗每周接受治疗,11只狗每周接受两次治疗。每次就诊时,采用改良的犬特应性皮炎程度和严重程度指数(m-CADESI)和改良的瘙痒视觉模拟量表(m-PVAS)。此外,业主满意度和潜在的不良影响进行了评估。结果:两组治疗后红斑及m-CADESI评分均有改善。然而,仅在治疗组2中观察到m-PVAS有统计学意义的降低。值得注意的是,与基线m-CADESI评分≤12的患者相比,m-PVAS的改善明显更大。在任何患者中均未观察到明显的不良反应,业主满意度从良好到极好。结论和相关性:局部冷冻治疗特应性指间皮炎,在适当的指示下,可能被认为是一种新颖、安全、有效的治疗选择,可以减少病变和瘙痒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Veterinary Science
Journal of Veterinary Science 农林科学-兽医学
CiteScore
3.10
自引率
5.60%
发文量
86
审稿时长
1.3 months
期刊介绍: The Journal of Veterinary Science (J Vet Sci) is devoted to the advancement and dissemination of scientific knowledge concerning veterinary sciences and related academic disciplines. It is an international journal indexed in the Thomson Scientific Web of Science, SCI-EXPANDED, Sci Search, BIOSIS Previews, Biological Abstracts, Focus on: Veterinary Science & Medicine, Zoological Record, PubMed /MEDLINE, Index Medicus, Pubmed Central, CAB Abstracts / Index Veterinarius, EBSCO, AGRIS and AGRICOLA. This journal published in English by the Korean Society of Veterinary Science (KSVS) being distributed worldwide.
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