Evaluation of Metastatic Insulinoma With Severe Hypoglycemia Using 68 Ga-Exendin-4 PET/CT.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-11-01 Epub Date: 2025-07-01 DOI:10.1097/RLU.0000000000006008

Jing Gao, Junyan Xu, Yun Liang, Jie Chen, Shaoli Song

引用次数: 0

Abstract

A 52-year-old man was pathologically diagnosed with a pancreatic neuroendocrine tumor (pNET) and synchronous liver metastasis through debulking surgery 2 years ago. Recently, the patient showed recurrent severe hypoglycemia after receiving multiple treatments. 68 Ga-Exendin-4 PET/CT imaging revealed diffuse uptake in the skeleton and other metastatic sites, which 68 Ga-DOTANOC PET/CT grossly underestimated. This case highlights the crucial role of 68 Ga-Exendin-4 in the comprehensive and accurate evaluation of metastatic insulinomas.

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68Ga-Exendin-4 PET/CT评价转移性胰岛素瘤伴严重低血糖

一名52岁的男性于2年前经病理诊断为胰腺神经内分泌肿瘤（pNET）并同步肝转移。近期，患者在多次治疗后复发严重低血糖。68Ga-Exendin-4 PET/CT成像显示骨骼和其他转移部位弥漫性摄取，68Ga-DOTANOC PET/CT严重低估了这一点。该病例强调了68Ga-Exendin-4在全面准确评估转移性胰岛素瘤中的重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.