M A H Suhaimi, S Taniselass, M K Md Arshad, Subash C B Gopinath, M F M Fathil, M M Ramli, I H Hasan
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引用次数: 0
Abstract
The escalating prevalence of cardiovascular diseases globally call for a low-cost monitoring technology for an immediate intervene and diagnoses. Advance multiplexed biosensors reinforced by graphene derivatives marks a significant progression in the field of cardiovascular health assessments. The graphene derived biosensors are designed specifically for fast detection of cardiac biomarkers with high precision to evaluate cardiovascular health. The graphene biocompatibility and fast signal transduction electronic properties provide an ideal foundation for the multiplexed technology. Despite the substantial potential of this multiplexed technologies, there remains a pressing need for further research and development to fully harness their capabilities in clinical environments. This study underscores the critical role of these biosensors in point of care applications and reviews the current landscape of research, highlighting significant progress made in graphene-based transduction and the recent trends in graphene production which give impact on biosensors performance. Key components are discussed include the assessment of vital cardiac biomarkers and the evolution of multiplex biosensing strategies that utilizes graphene nanomaterials. In summary, this review provides a comprehensive overview of the latest advancements in multi-analyte detection for cardiac healthcare. It outlines the key challenges encountered while proposing potential strategies to improve the effectiveness of multiplex biosensing platforms, thereby supporting the advancement of cardiac diagnostics. The potential of multiplexed biosensing technology leads to enhance diagnostic capabilities while reducing healthcare costs represents a significant advancement in cardiovascular healthcare, particularly for point-of-care applications.
期刊介绍：
Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area.
This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following:
· chemical analysis;
· instrumentation;
· chemometrics;
· analytical biochemistry;
· medicinal analysis;
· forensics;
· environmental sciences;
· applied physics;
· and material science.
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