Laparoscopic multi-bipolar radiofrequency ablation of fibroids: impact on quality of life.

IF 2.1 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Archives of Gynecology and Obstetrics Pub Date : 2025-06-28 DOI:10.1007/s00404-025-08082-8

Raphael Niddam, Antoine Netter, Blandine Courbière, Aubert Agostini, Laura Miquel

{"title":"Laparoscopic multi-bipolar radiofrequency ablation of fibroids: impact on quality of life.","authors":"Raphael Niddam, Antoine Netter, Blandine Courbière, Aubert Agostini, Laura Miquel","doi":"10.1007/s00404-025-08082-8","DOIUrl":null,"url":null,"abstract":"Objective: To evaluate the effectiveness of multi-bipolar radiofrequency ablation compared to standard laparoscopic myomectomy in treating uterine fibroids, focusing on women's quality of life.Design: Retrospective observational cohort study.Setting: La Conception Hospital, APHM-Marseille, France.Patients: 50 women with symptomatic fibroids treated between December 2021 and December 2023.Intervention: Laparoscopic radiofrequency ablation or conventional laparoscopic myomectomy.Measurements and main results: After excluding patients who did not complete the preoperative quality-of-life questionnaire, 34 underwent myomectomy and 16 radiofrequency ablation. At 3 months, no significant differences were observed in HRQOL improvement (9.2 ± 34.3 vs 24.2 ± 28.2, p = 0.14), SSS (- 27.5 ± 31.5 vs - 23.3 ± 33, p = 0.66), or FSFI (0.9 ± 14.7 vs - 1.5 ± 10.8, p = 0.40). The 6-month outcomes also showed no significant difference. Baseline fibroid-specific quality of life was significantly and negatively associated with improvement (p < 0.05).Conclusion: Both procedures improved quality of life and reduced fibroid-related symptoms at 3 and 6 months, with no significant difference. Myolysis showed fewer peri- and postoperative complications, suggesting a better safety profile and potential as a conservative treatment option.Trial registration: The ethics committee of Aix Marseille University approved this study on April 18, 2024, under the reference number 2024-04-18-08.","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Gynecology and Obstetrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00404-025-08082-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To evaluate the effectiveness of multi-bipolar radiofrequency ablation compared to standard laparoscopic myomectomy in treating uterine fibroids, focusing on women's quality of life.

Design: Retrospective observational cohort study.

Setting: La Conception Hospital, APHM-Marseille, France.

Patients: 50 women with symptomatic fibroids treated between December 2021 and December 2023.

Intervention: Laparoscopic radiofrequency ablation or conventional laparoscopic myomectomy.

Measurements and main results: After excluding patients who did not complete the preoperative quality-of-life questionnaire, 34 underwent myomectomy and 16 radiofrequency ablation. At 3 months, no significant differences were observed in HRQOL improvement (9.2 ± 34.3 vs 24.2 ± 28.2, p = 0.14), SSS (- 27.5 ± 31.5 vs - 23.3 ± 33, p = 0.66), or FSFI (0.9 ± 14.7 vs - 1.5 ± 10.8, p = 0.40). The 6-month outcomes also showed no significant difference. Baseline fibroid-specific quality of life was significantly and negatively associated with improvement (p < 0.05).

Conclusion: Both procedures improved quality of life and reduced fibroid-related symptoms at 3 and 6 months, with no significant difference. Myolysis showed fewer peri- and postoperative complications, suggesting a better safety profile and potential as a conservative treatment option.

Trial registration: The ethics committee of Aix Marseille University approved this study on April 18, 2024, under the reference number 2024-04-18-08.

查看原文本刊更多论文

腹腔镜多重双极射频消融肌瘤：对生活质量的影响。

目的：评价多极射频消融术与标准腹腔镜子宫肌瘤切除术治疗子宫肌瘤的疗效，重点观察妇女的生活质量。设计：回顾性观察队列研究。地点：法国马赛aphm医院概念医院。患者：在2021年12月至2023年12月期间接受治疗的50名有症状的肌瘤妇女。干预：腹腔镜射频消融或常规腹腔镜子宫肌瘤切除术。测量和主要结果：在排除未完成术前生活质量问卷的患者后，34例患者行子宫肌瘤切除术，16例行射频消融术。3个月时，HRQOL改善（9.2±34.3 vs 24.2±28.2,p = 0.14）、SSS（- 27.5±31.5 vs - 23.3±33,p = 0.66）、FSFI（0.9±14.7 vs - 1.5±10.8,p = 0.40）无显著差异。6个月的结果也无显著差异。基线肌瘤特异性生活质量与改善显著负相关(p)。结论：两种手术在3个月和6个月时改善了生活质量并减轻了肌瘤相关症状，无显著差异。肌溶解术的围手术期和术后并发症较少，提示其安全性较好，有可能作为保守治疗方案。试验注册：艾克斯马赛大学伦理委员会于2024年4月18日批准本研究，参考文献号：2024-04-18-08。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Archives of Gynecology and Obstetrics 医学-妇产科学

CiteScore

4.70

自引率

15.40%

发文量

493

审稿时长

1 months

期刊介绍： Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.