The first case report of an intraosseous hemangioma complicated by Prevotella bivia infection

Abstract

Intraosseous hemangiomas are rare benign vascular tumors that occur within the bone. Prevotella bivia is an anaerobic, gram-negative rod that is part of the normal microbiota of the gastrointestinal and urogenital tract as well as the oral cavity, but it rarely causes bone infections. This case report presents a patient with a history of dental infection who was initially diagnosed radiologically with non-ossifying fibroma (NOF) in the knee. Histopathology and anaerobic culture identified the lesion as an intraosseous hemangioma infected with P.bivia. The patient was treated with amoxicillin-clavulanic acid and metronidazole. This case report underscores the importance of considering rare pathogens in the differential diagnosis of bone lesions when clinical and radiological findings do not align.