The relationship between gait profile and spino-pelvic alignment in patients with adolescent idiopathic scoliosis of Lenke type 1 and 5

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Clinical Neuroscience Pub Date : 2025-07-01 DOI:10.1016/j.jocn.2025.111444

Minjun Choi, Tae Sik Goh, Jung Sub Lee

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引用次数: 0

Abstract

Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional structural deformity of the spine. While studies have reported gait abnormalities in AIS patients and their impact on patients’ quality of life, the interrelationship between the sagittal spino-pelvic alignment and gait kinematics has not yet been elucidated. The purpose of this study is to investigate the association between gait profile and sagittal alignment in AIS patients, especially with Lenke type 1 and 5 curve deformities.

The study group consisted of 111 AIS patients and sixty healthy controls. Standing spinal radiographs and gait analysis were performed for all participants. Gait parameters included gait speed, step length, stance phase, cadence, single leg support, double legs support, gait asymmetry (GA), and phase coordination index (PCI). Radiographic parameters included pelvic tilt (PT), sacral slope (SS), pelvic incidence (PI), thoracic kyphosis (TK), lumbar lordosis (LL), Cobb’s major curve angle, sagittal vertical axis (SVA), and coronal balance (CB).

There were statistically significant differences between the AIS group and the control in gait speed, step length, cadence, single leg support, double legs support, GA, PT, TK, SVA, and CB. However, no significant difference was observed between the groups in stance phase, PCI, SS, PI, and LL (p > 0.05). In addition, correlation analysis revealed significant relationships between the following pairs of gait and sagittal alignment parameters in the AIS patients; step length was related with SS, PT, and LL, PCI with CB, GA with TK and CB. Multiple regression analysis of gait and sagittal profile also indicated that PT and SS are accurate predictors of step length and CB is a predictor of GA.

In conclusion, our findings demonstrated that there are significant differences in gait kinematics and sagittal spino-pelvic alignment between the AIS patients and healthy population and that these parameters are closely correlated in the AIS patients.

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青少年特发性Lenke 1型和5型脊柱侧凸患者步态特征与脊柱-骨盆线的关系

青少年特发性脊柱侧凸是一种复杂的脊柱三维结构畸形。虽然有研究报道了AIS患者的步态异常及其对患者生活质量的影响，但矢状面脊柱-骨盆对齐与步态运动学之间的相互关系尚未得到阐明。本研究的目的是探讨AIS患者，特别是Lenke 1型和5型弯曲畸形患者的步态特征与矢状面对齐之间的关系。研究组由111名AIS患者和60名健康对照者组成。对所有参与者进行站立脊柱x线片和步态分析。步态参数包括步态速度、步长、站立相位、节奏、单腿支撑、双腿支撑、步态不对称（GA）、相协调指数（PCI）。影像学参数包括骨盆倾斜（PT）、骶骨倾斜（SS）、骨盆发生率（PI）、胸后凸（TK）、腰椎前凸（LL）、Cobb主曲线角、矢状垂直轴（SVA）和冠状平衡（CB）。AIS组与对照组在步速、步长、步速、单腿支撑、双腿支撑、GA、PT、TK、SVA、CB等方面差异均有统计学意义。然而，两组在站立期、PCI、SS、PI和LL方面无显著差异(p >；0.05)。此外，相关分析显示，AIS患者的以下步态对与矢状面对齐参数之间存在显著相关性；步长与SS、PT、LL相关，PCI与CB相关，GA与TK、CB相关。步态和矢状面分布的多元回归分析也表明PT和SS是步长的准确预测因子，CB是GA的预测因子。总之，我们的研究结果表明，AIS患者与健康人群在步态运动学和矢状面脊柱-骨盆对齐方面存在显著差异，这些参数在AIS患者中密切相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Neuroscience 医学-临床神经学

CiteScore

4.50

自引率

0.00%

发文量

402

审稿时长

40 days

期刊介绍： This International journal, Journal of Clinical Neuroscience, publishes articles on clinical neurosurgery and neurology and the related neurosciences such as neuro-pathology, neuro-radiology, neuro-ophthalmology and neuro-physiology. The journal has a broad International perspective, and emphasises the advances occurring in Asia, the Pacific Rim region, Europe and North America. The Journal acts as a focus for publication of major clinical and laboratory research, as well as publishing solicited manuscripts on specific subjects from experts, case reports and other information of interest to clinicians working in the clinical neurosciences.