Sulfonated Phosphine-Palladium/Bisguanidinium Ion Pair Catalyzed Enantioselective Allylic Amination

Abstract

In this study, we successfully developed ion pair catalysts consisting of chiral bisguanidinium (BG) cations and non-chiral sulphonated phosphine-palladium complexes as counterions. These ion pairs catalyzed allylic alkylation reactions with excellent enantioselectivities. Furthermore, these reactions can be easily performed on a gram-scale, demonstrating their potential for industrial applications. We were able to obtain ¹H NMR of the ion pair catalyst and identified the ³¹P NMR of the sulphonated phosphine-palladium complex.