Plateletpheresis for treating essential thrombocythemia that developed during pregnancy: A case report

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI:10.1016/j.tjog.2025.01.008

Naohisa Masuko , Kenji Tanimura , Koki Moriuchi , Tomomi Kita , Kenta Obata , Sonoko Suda , Hitomi Imafuku , Masashi Deguchi , Keiji Kurata , Kimikazu Yakushijin , Keiji Kono , Takuya Kawakatsu , Yoshito Terai

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引用次数: 0

Abstract

Objective

Essential thrombocythemia (ET), a life-threatening disease, is associated with increased risks of hemorrhagic and thromboembolic complications. In particular, ET during pregnancy is rare and associated with an increased risk of obstetric complications. Drug therapies are frequently administered for managing pregnant women with ET, and plateletpheresis is considered to reduce platelet (PLT) counts rapidly.

Case report

A 28-year-old pregnant woman was referred to our hospital at 37 + 0/7 gestational weeks (GWs) due to severe thrombocythemia. She underwent plateletpheresis at 37 + 4/7 GWs because thrombocythemia was exacerbated. She delivered vaginally at 38 + 0/7 GWs without hemorrhagic or thromboembolic complications. She was diagnosed with ET based on a bone marrow biopsy, and ET gradually improved with medication. Thus, she and her baby were discharged without complications.

Conclusion

Plateletpheresis is useful for preventing hemorrhagic and thromboembolic complications at delivery in pregnant women with ET and severe thrombocythemia during the antepartum period.

查看原文本刊更多论文

采血小板治疗妊娠期间发生的原发性血小板增多症：1例报告

目的：原发性血小板增多症（ET）是一种危及生命的疾病，与出血和血栓栓塞并发症的风险增加有关。特别是，妊娠期ET很少见，并与产科并发症的风险增加有关。药物治疗经常用于治疗ET的孕妇，血小板提取被认为可以迅速降低血小板（PLT）计数。病例报告一名28岁孕妇因严重的血小板增多症于37 + 0/7妊娠周（GWs）转诊至我院。由于血小板增多症加重，她在37 + 4/7 gw时接受了血小板抽血。她在38 + 0/7 gw时顺产，无出血或血栓栓塞并发症。根据骨髓活检，她被诊断为ET， ET在药物治疗后逐渐好转。因此，她和她的孩子出院了，没有并发症。结论血小板抽血可预防ET合并严重血小板增多症孕妇产前出血及血栓栓塞并发症的发生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.