Evaluation of PLA gyroid scaffold for long bone fracture treatment: numerical and experimental study

IF 3.5 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-06-25 DOI:10.1016/j.jmbbm.2025.107110

A. Sabik, A. Andrzejewska-Sroka, K. Daszkiewicz, M. Rucka, W. Witkowski

引用次数: 0

Abstract

In the paper the load capacity and mechanoregulation properties of a 3D printed gyroid scaffold made of pure PLA implanted into the long bone defect are assessed. The constitutive law of the material is estimated based on experimental data and a finite element method (FEM) model. Within the FEM, the bone healing process is simulated, considering the biphasic nature of the tissues and making use of the Prendergast mechanoregulation theory, where the mechanical stimuli include octahedral shear strain and interstitial fluid velocity. The computations are performed in Abaqus software. It is shown that the strength of pure PLA is sufficient for the treatment of long bone fractures. The gyroid scaffold provides a low mechanical stimulus in the fracture gap and reduces adverse strain and velocity concentration between the fractured bone fragments.

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PLA旋转支架治疗长骨骨折的评价：数值与实验研究

本文对纯聚乳酸3D打印陀螺支架植入长骨缺损的承载能力和力学调节性能进行了评估。基于实验数据和有限元模型估算了材料的本构规律。在FEM中，考虑到组织的双相性质并利用Prendergast力学调节理论，模拟骨愈合过程，其中力学刺激包括八面体剪切应变和间质流体速度。在Abaqus软件中进行计算。结果表明，纯聚乳酸的强度足以治疗长骨骨折。旋转支架在骨折间隙提供低机械刺激，减少骨折碎片之间的不良应变和速度集中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.