Therapeutic effects of traditional Chinese medicine fumigation plus Yang-He decoction for patients with ankylosing spondylitis: systematic review and network meta-analysis
IF 2.2 4区 医学Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE
Xuan Li , Peng Dai , Jing Mao , Jiewen Deng , Yunnan Li
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引用次数: 0
Abstract
Introduction
To compare and rank the therapeutic effects of traditional Chinese medicine fumigating (TCMF) plus Yang-He decoction (YHD), TCMF plus acupuncture, TCMF, YHD, acupuncture, and Western medicine (WM) in patients with ankylosing spondylitis (AS).
Methods
The PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Wanfang, and VIP electronic databases were searched for eligible randomised controlled trials (RCTs) from their inception until April 2023. The primary endpoint was the efficacy rate.
Results
Nineteen RCTs involving 1 432 AS patients were selected. The surface under the cumulative ranking (SUCRA) probabilities indicated TCMF plus acupuncture (SUCRA: 78%) and TCMF plus YHD (SUCRA: 71%) exhibited relatively better efficacy. TCMF plus WM versus WM yielded a lower Visual Analogue Scale (VAS) score (P = 0.043), shorter morning stiffness time (MST) (P = 0.002), and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (P = 0.003). Moreover, YHD plus WM versus WM was associated with a lower VAS score (P < 0.001), finger-floor distance (P < 0.001), pillow-wall distance (PWD) (P = 0.001), Bath Ankylosing Spondylitis Functional Index (BASFI) (P = 0.001), erythrocyte sedimentation rate (P < 0.001), or C-reactive protein (CRP) (P < 0.001), elevated Schober test (P < 0.001), thoracic expansion (P < 0.001), spinal column activity (SCA) (P < 0.001), and shorter MST (P < 0.001). TCMF plus YHD versus WM achieved a lower VAS score (P = 0.002), BASDAI (P < 0.001), BASFI (P < 0.001) or CRP (P = 0.038), and elevated SCA (P = 0.002). TCMF plus acupuncture versus WM showed lower VAS score (P < 0.001) and BASFI (P < 0.001). Finally, TCMF plus acupuncture versus acupuncture showed lower PWD (P = 0.004) and CRP (P = 0.031).
Conclusion
TCMF plus acupuncture and TCMF plus YHD provided better therapeutic effects in patients with AS.
期刊介绍:
The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.