Maternal Ophthalmic Artery Resistance in Pregnancies With Pre-Eclampsia Compared to Normotensive Participants

Q3 Medicine
Mahnaz Ranjkesh, Mohammad Khalafi, Vahid Salehi, Shahab Abdi, Mahsa Karbasi, Esmaeil Gharepapagh
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Abstract

Objectives

The condition known as pre-eclampsia (PE) is characterised by hemodynamic changes that can impact the ophthalmic artery, a branch of the internal carotid artery. In this study, we aimed to compare the ophthalmic artery resistance in pregnant participants with PE to those with normal blood pressure.

Materials and Methods

In this cross sectional study, the hemodynamic changes of the maternal ophthalmic artery were analysed using spectral Doppler ultrasound. The research included 50 normotensive pregnant participants matched for gestational age with 50 pregnant participants with PE. The study measured peak systolic velocity (PSV), end-diastolic velocity (EDV), S/D ratio, Resistance Index (RI) and Pulsatility Index (PI) to determine any differences between the two groups.

Results

A comparison of PSV parameters in two groups did not reveal any statistically significant difference (p > 0.05). However, Doppler findings were significantly lower for pregnant participants with PE than those with normal blood pressure in terms of RI (p = 0.008), PI (p < 0.001) and S/D ratio (p = 0.002). Conversely, EDV was higher for pregnant participants with PE (p = 0.032).

Conclusion

This study found significant differences in the ophthalmic artery Doppler indices between pregnant participants with PE and those with normal blood pressure. Specifically, lower RI, PI and S/D ratio, as well as a higher EDV, were observed in the PE group. These findings suggest altered blood flow dynamics in PE. Clinically, spectral Doppler ultrasound of the ophthalmic artery could be a useful, non-invasive tool for detecting and monitoring haemodynamic changes in PE. Given its accessibility and repeatability, it could help identify PE earlier, especially in settings where more advanced diagnostic tools are unavailable.

与血压正常的孕妇相比,先兆子痫孕妇的眼动脉阻力
目的先兆子痫(PE)的特点是血流动力学改变,可影响眼动脉(颈内动脉的一个分支)。在这项研究中,我们的目的是比较妊娠期PE患者与正常血压患者的眼动脉阻力。材料与方法本研究采用多普勒超声对产妇眼动脉血流动力学变化进行了分析。该研究包括50名孕龄正常的孕妇和50名PE孕妇。研究测量了峰值收缩速度(PSV)、舒张末期速度(EDV)、S/D比、阻力指数(RI)和脉搏指数(PI),以确定两组之间的差异。结果两组患者PSV参数比较,差异无统计学意义(p > 0.05)。然而,与血压正常的孕妇相比,患有PE的孕妇在RI (p = 0.008)、PI (p < 0.001)和S/D比(p = 0.002)方面的多普勒结果明显较低。相反,患有PE的孕妇EDV更高(p = 0.032)。结论妊娠PE患者的眼动脉多普勒指数与血压正常的孕妇有显著差异。具体而言,PE组的RI、PI和S/D比较低,EDV较高。这些发现提示PE患者血流动力学改变。临床上,眼动脉多普勒超声是一种有用的、无创的检测和监测PE血流动力学变化的工具。鉴于其可访问性和可重复性,它可以帮助更早地识别PE,特别是在无法获得更高级诊断工具的环境中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Australasian Journal of Ultrasound in Medicine
Australasian Journal of Ultrasound in Medicine Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.90
自引率
0.00%
发文量
40
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