Mark S Keller, Eric Morth, Thomas C Smits, Simon Warchol, Grace Guo, Qianwen Wang, Robert Krueger, Hanspeter Pfister, Nils Gehlenborg
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引用次数: 0
Abstract
Recent advancements have enabled tissue samples to be profiled at the unprecedented level of detail of a single cell. Analysis of this data has enabled discoveries that are relevant to understanding disease and developing therapeutics. Large-scale profiling efforts are underway which aim to generate 'atlas' resources that catalog cellular archetypes including biomarkers and spatial locations. While the problem of cellular data visualization is not new, the size, resolution, and heterogeneity of single-cell atlas datasets presents challenges and opportunities. We survey the usage of visualization to interpret single-cell atlas datasets by assessing over 1,800 figure panels from 45 biological publications. We intend for this report to serve as a foundational resource for the visualization community as atlas-scale single-cell datasets are emerging rapidly with aims of advancing our understanding of biological function in health and disease.
期刊介绍:
IEEE Computer Graphics and Applications (CG&A) bridges the theory and practice of computer graphics, visualization, virtual and augmented reality, and HCI. From specific algorithms to full system implementations, CG&A offers a unique combination of peer-reviewed feature articles and informal departments. Theme issues guest edited by leading researchers in their fields track the latest developments and trends in computer-generated graphical content, while tutorials and surveys provide a broad overview of interesting and timely topics. Regular departments further explore the core areas of graphics as well as extend into topics such as usability, education, history, and opinion. Each issue, the story of our cover focuses on creative applications of the technology by an artist or designer. Published six times a year, CG&A is indispensable reading for people working at the leading edge of computer-generated graphics technology and its applications in everything from business to the arts.