Anesthetic mortality in swine: a multicenter retrospective analysis

IF 1.9 2区农林科学 Q2 VETERINARY SCIENCES

Veterinary anaesthesia and analgesia Pub Date : 2025-06-10 DOI:10.1016/j.vaa.2025.06.001

Sarah R. Camlic , Rachel A. Reed , Stephanie C. Dantino , Stephanie A. Hon , Stephanie A. Kleine , Christopher K. Smith , Alanna N. Johnson , Jane E. Quandt , Michele Barletta , Daniel M. Sakai

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引用次数: 0

Abstract

Objective

To investigate the incidence of anesthesia and sedation-related mortality in domestic swine and identify any associated risk factors.

Study design

Multicenter retrospective cohort study.

Animals

A total of 1849 pigs.

Methods

Medical records of pigs undergoing anesthesia or sedation at four veterinary teaching hospitals between August 2018 and July 2023 were reviewed. Variables evaluated included signalment, American Society of Anesthesiologists (ASA) Physical Status Classification, emergency designation, duration of anesthesia or sedation, time of day at anesthesia or sedation initiation, anesthetic agents used, airway management (intubation versus facemask), and 24 hour outcome. Outcome was classified as alive, dead, or euthanized. Each variable was analyzed using univariate logistic regression, with proportions and odds ratios calculated with 95% confidence intervals. Statistical significance was set at p < 0.05.

Results

A total of 1852 records were reviewed, with three records excluded. Of the remaining 1849 cases, 69 (3.7%) were euthanized due to poor prognosis. The overall mortality rate for the remaining pigs was 0.96%, with 17 pigs dead 24 hours postanesthesia. Factors associated with increased odds of mortality [p value; odds ratio (95% confidence interval)] included ASA III–V [p < 0.001; 9.8 (3.6–26.8)], emergency procedure [p < 0.001; 13 (4.0–34.3)], and after-hours procedures [p < 0.001; 5.6 (1.2–25.2)]. No other factors were associated with increased or decreased odds of mortality.

Conclusions and clinical relevance

This is the first study to report the incidence of mortality associated with anesthesia in porcine patients. In the studied population, higher ASA as well as emergency and after-hours procedures were associated with an increase in mortality rate.

查看原文本刊更多论文

猪麻醉死亡率：一项多中心回顾性分析。

目的：调查家猪麻醉及镇静相关死亡的发生率，并找出相关的危险因素。研究设计：多中心回顾性队列研究。动物：共有1849头猪。方法：回顾2018年8月至2023年7月4家兽医教学医院麻醉或镇静猪的病历。评估的变量包括信号、美国麻醉医师协会（ASA）身体状态分类、急诊名称、麻醉或镇静持续时间、麻醉或镇静开始的时间、使用的麻醉剂、气道管理（插管还是面罩）和24小时结果。结果分为活着、死亡和安乐死。每个变量使用单变量逻辑回归分析，比例和优势比以95%置信区间计算。p < 0.05为差异有统计学意义。结果：共审核记录1852份，排除3份。其余1849例中，69例（3.7%）因预后不良而被安乐死。其余猪的总死亡率为0.96%，麻醉后24小时死亡17头。与死亡率增加有关的因素[p值；优势比（95%置信区间）]包括ASA III-V [p < 0.001；9.8(3.6-26.8)]，急诊处理[p < 0.001；13(4.0-34.3)]和下班后处理[p < 0.001；5.6(1.2 - -25.2)]。没有其他因素与死亡率的增加或减少有关。结论和临床意义：这是第一个报道猪患者麻醉相关死亡率的研究。在研究人群中，较高的ASA以及急诊和下班后手术与死亡率增加有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary anaesthesia and analgesia 农林科学-兽医学

CiteScore

3.10

自引率

17.60%

发文量

审稿时长

97 days

期刊介绍： Veterinary Anaesthesia and Analgesia is the official journal of the Association of Veterinary Anaesthetists, the American College of Veterinary Anesthesia and Analgesia and the European College of Veterinary Anaesthesia and Analgesia. Its purpose is the publication of original, peer reviewed articles covering all branches of anaesthesia and the relief of pain in animals. Articles concerned with the following subjects related to anaesthesia and analgesia are also welcome: the basic sciences; pathophysiology of disease as it relates to anaesthetic management equipment intensive care chemical restraint of animals including laboratory animals, wildlife and exotic animals welfare issues associated with pain and distress education in veterinary anaesthesia and analgesia. Review articles, special articles, and historical notes will also be published, along with editorials, case reports in the form of letters to the editor, and book reviews. There is also an active correspondence section.