Adverse childhood experiences and disengagement from HIV care: a case-cohort study in Tanzania.

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES
Sydney Tucker, Solis Winters, Emmanuel Katabaro, Matilda Mlowe, Patrick Bradshaw, Jennifer Ahern, John Colford, Laura Packel, Susan Hillis, Amon Sabasaba, Prosper Njau, Sandra I McCoy
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引用次数: 0

Abstract

Adverse childhood experiences (ACEs) can have lasting, detrimental effects throughout the lifespan and may influence engagement in health care. We conducted a case-cohort study in Tanzania to estimate the association between ACEs and disengagement from HIV care 12 months after initiating antiretroviral therapy (ART) among 217 adults (26 cases and 191 sub-cohort participants). Experiencing one, two, three, and four additional ACEs was significantly associated with 28% (RRa= 1.24; 95% CI: 1.05, 1.44; p-value < 0.01), 64% (RRa=1.64; 95% CI: 1.22, 2.20), 110% (RRa=2.10; 95% CI: 1.35, 3.26), and 168% (RRa=2.68; 95% CI: 1.49, 4.38) increases in the risk of disengagement from HIV care, respectively. These findings call for integrated trauma-informed mental health services within HIV care to end HIV/AIDS as a public health threat.

不良的童年经历和脱离艾滋病毒护理:坦桑尼亚的病例队列研究。
不良的童年经历(ace)可能在整个生命周期中产生持久的有害影响,并可能影响对卫生保健的参与。我们在坦桑尼亚进行了一项病例队列研究,以估计217名成年人(26例和191名亚队列参与者)在开始抗逆转录病毒治疗(ART) 12个月后ace与脱离HIV护理之间的关系。另外经历1、2、3和4次ace的患者与28%显著相关(RRa= 1.24;95% ci: 1.05, 1.44;假定值= 1.64;95% CI: 1.22, 2.20), 110% (RRa=2.10;95% CI: 1.35, 3.26)和168% (RRa=2.68;95% CI: 1.49, 4.38)分别增加了脱离艾滋病毒护理的风险。这些发现呼吁在艾滋病毒护理中提供综合创伤知情精神卫生服务,以结束艾滋病毒/艾滋病作为公共卫生威胁。
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来源期刊
AIDS Research and Therapy
AIDS Research and Therapy INFECTIOUS DISEASES-
CiteScore
3.80
自引率
4.50%
发文量
51
审稿时长
16 weeks
期刊介绍: AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered
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