Recent advancements of pyrimidine chemistry thriving deeper into drug discovery

Abstract

Pyrimidine-containing organic compounds have been widely studied and are highly important. With this intent, a genuine attempt has been made to reflect the various synthetic developments and biological perspectives of pyrimidine-containing analogues leading to drug design and discovery. The synthetic strategies give the in-depth route of generating pyrimidines. The biology includes antiviral, antioxidant, anti-inflammatory, and anticancer, activities. By going in depth with all the studies made by various researchers, the scope of pyrimidine is vast. The extensive properties exhibited by various compounds reveal the ability of pyrimidines to act as potent drugs in future. Most of the compounds showed better performance than the standard drugs available. Therefore, the need for reviewing all the recent advances in pyrimidine-related chemistry was necessary and it will aid to boost the research both in academic and pharma sector.