[Features of clinical and laboratory parameters in elderly patients with acute coronary syndrome.]

Abstract

The inclusion of elderly patients in randomized clinical trials does not reflect the age-related association in coronary heart disease. At the same time, there are few scientific papers devoted to clinical and laboratory factors characteristic of the development of acute coronary syndrome (ACS) in this age category. Timely assessment of clinical and biochemical blood parameters in elderly patients is of great importance in preventing complications that naturally increase in them, significantly affects treatment tactics and the possibility of using generally accepted approaches when choosing drug therapy. From these positions, our study showed the special role of triglycerides and glucose in the development of ACS in elderly patients. A joint assessment of the median serum creatinine (sCr) concentration and the nature of its change during stay in the coronary care unit was carried out, which allowed us to conclude that the stratification risk of mortality was reduced. In patients with ACS, the daily value of sCr and the nature of its change are stronger predictors of hospital mortality than only the initial value of sCr. The results of the study suggest that it is recommended to evaluate serum creatinine to ensure a more accurate and dynamic risk stratification in elderly patients with ACS.