The Role of Combined C-reactive Protein and Albumin Indices in Predicting Prolonged Hospital Stay in Acute Pancreatitis: A Prospective Observational Study.
Abdullah Algin, Serdar Ozdemir, Mustafa Ahmet Afacan, Kaan Yusufoglu, Abuzer Ozkan
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引用次数: 0
Abstract
Objective: To evaluate the predictive ability of indices based on the combination of C-reactive protein (CRP) and albumin, namely the CRP/albumin ratio (CAR), Glasgow prognostic score (GPS), and modified GPS (mGPS), for prolonged hospital stay in patients with acute pancreatitis.
Methods: This prospective observational study was conducted on patients monitored in the emergency department of a tertiary university hospital. The patients' demographic data, vital signs, laboratory parameters, comorbidities, and length of hospital stay were prospectively recorded. Based on their length of hospital stay, the patients were divided into two groups: prolonged stay (>7 days) and non-prolonged stay. The indices were compared between these groups.
Results: There were statistically significant differences in CAR, GPS, and mGPS between the prolonged and non-prolonged hospital stay groups (p<0.001 for all; chi-square test). The area under the curve values of CAR, GPS, and mGPS were calculated as 0.677 [95% confidence interval (CI): 0.601-0.753, p<0.001], 0.637 (95% CI: 0.570-0.704, p<0.001), and 0.671 (95% CI: 0.602-0.740, p<0.001), respectively. According to multivariate analysis, CAR [odds ratio (OR)=1.017, 95% CI (1.003-1.03), p=0.015], GPS [OR=2.894, 95% CI (1.632-5.13), p<0.001], and mGPS [OR=3.757, 95% CI (2.108-6.70), p<0.001] were found to be independent predictors of prolonged hospital stay.
Conclusions: CAR, GPS, and mGPS are independent predictors of prolonged hospital stay in patients with acute pancreatitis. The findings also suggest that incorporating CRP levels into prognostic calculations may yield more accurate results compared to scores based solely on albumin levels.
期刊介绍：
The Medeniyet Medical Journal (Medeniyet Med J) is an open access, peer-reviewed, and scientific journal of Istanbul Medeniyet University Faculty of Medicine on various academic disciplines in medicine, which is published in English four times a year, in March, June, September, and December by a group of academics. Medeniyet Medical Journal is the continuation of Göztepe Medical Journal (ISSN: 1300-526X) which was started publishing in 1985. It changed the name as Medeniyet Medical Journal in 2015. Submission and publication are free of charge. No fees are asked from the authors for evaluation or publication process. All published articles are available online in the journal website (www.medeniyetmedicaljournal.org) without any fee. The journal publishes intradisciplinary or interdisciplinary clinical, experimental, and basic researches as well as original case reports, reviews, invited reviews, or letters to the editor, Being published since 1985, the Medeniyet Med J recognizes that the best science should lead to better lives based on the fact that the medicine should serve to the needs of society, and knowledge should transform society. The journal aims to address current issues at both national and international levels, start debates, and exert an influence on decision-makers all over the world by integrating science in everyday life. Medeniyet Med J is committed to serve the public and influence people’s lives in a positive way by making science widely accessible. Believing that the only goal is improving lives, and research has an impact on people’s lives, we select the best research papers in line with this goal.
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