Promoting HPV Vaccination in College Students Through Educational Video: Results from a Randomized Trial.

IF 5.2 3区 医学 Q1 IMMUNOLOGY
Vaccines Pub Date : 2025-05-30 DOI:10.3390/vaccines13060587
Angela Chia-Chen Chen, Kimberly Arcoleo, Alli Walsh
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Abstract

Objectives: Human papillomavirus (HPV) is a leading cause of several cancers, yet HPV vaccination rates among U.S. young adults remain low. This study evaluated the effect of a brief educational video, co-developed with college students, in increasing HPV vaccination intention among unvaccinated college-aged individuals.

Methods: A two-group randomized controlled trial was conducted among 215 college students aged 18-26 who had not received the HPV vaccine. Participants were randomly assigned to two interventions: a video group (n = 111) or a leaflet group that viewed a CDC-based educational sheet (n = 104). Pre- and post-intervention surveys assessed HPV knowledge, perceived risk, facilitators and barriers to vaccination, cultural beliefs, and vaccination intention. Data were analyzed using descriptive statistics, t-tests, Wilcoxon Signed-Rank, and Mann-Whitney U tests.

Results: At baseline, approximately 56% of the sample (n = 215; mean age = 23.5, 71.2% male) have learned about HPV in the past. Although both groups improved in HPV knowledge, perceived lower risk, and cultural beliefs, between-group differences in these theoretical mediators were not statistically significant. Vaccination intention (those who responded "Yes" or "Maybe") increased by 10.8% in the video group but decreased by 11.6% in the leaflet group following the intervention; the difference between the two groups was statistically significant (p = 0.03).

Conclusions: A brief, participatory, and theory-based video significantly increased HPV vaccination intent among unvaccinated college students. Compared to the leaflet intervention, the video intervention offers a promising and scalable public health strategy for promoting HPV vaccination in this high-risk population.

通过教育视频促进大学生接种HPV疫苗:一项随机试验的结果。
目的:人乳头瘤病毒(HPV)是几种癌症的主要原因,但美国年轻人的HPV疫苗接种率仍然很低。本研究评估了与大学生共同制作的简短教育视频在提高未接种疫苗的大学年龄个体的HPV疫苗接种意愿方面的效果。方法:对215名未接种HPV疫苗的18-26岁大学生进行两组随机对照试验。参与者被随机分配到两个干预组:一个是视频组(n = 111),另一个是传单组(n = 104)。干预前和干预后调查评估了HPV知识、感知风险、疫苗接种的促进因素和障碍、文化信仰和疫苗接种意图。数据分析采用描述性统计、t检验、Wilcoxon sign - rank检验和Mann-Whitney U检验。结果:基线时,约56%的样本(n = 215;平均年龄23.5岁,71.2%男性)过去曾了解HPV。尽管两组在HPV知识、感知到的低风险和文化信仰方面都有所提高,但这些理论中介因素的组间差异没有统计学意义。干预后,视频组的疫苗接种意向(回答“是”或“可能”的人)增加了10.8%,但传单组减少了11.6%;两组间差异有统计学意义(p = 0.03)。结论:一个简短的、参与性的、基于理论的视频显著提高了未接种HPV疫苗的大学生的疫苗接种意愿。与单张干预相比,视频干预为在这一高危人群中促进HPV疫苗接种提供了一种有前途和可扩展的公共卫生策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Vaccines
Vaccines Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
8.90
自引率
16.70%
发文量
1853
审稿时长
18.06 days
期刊介绍: Vaccines (ISSN 2076-393X) is an international, peer-reviewed open access journal focused on laboratory and clinical vaccine research, utilization and immunization. Vaccines publishes high quality reviews, regular research papers, communications and case reports.
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