Centers for Medical Countermeasures against Radiation Consortium: Past, Present, and Beyond.

IF 2.7 3区医学 Q2 BIOLOGY

Radiation research Pub Date : 2025-09-01 DOI:10.1667/RADE-24-00275.1

Lanyn P Taliaferro, David J Brenner, Sally A Amundson, Guy Garty, Yuji Zhang, Erika W Davies, France Carrier, Joel R Ross, J Mark Cline, Nelson J Chao

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引用次数: 0

Abstract

The Centers for Medical Countermeasures against Radiation Consortium (CMCRC) has provided a strong research foundation for the radiobiology science that will follow. After 20 years, however, the CMCRC will continue to conduct research on preparedness in niche areas of radiobiology and advanced product development, many of which were initiated by the CMCRC. This manuscript offers a review of past and current strategies and advancements in medical countermeasures to address radiation injuries, carried out by the CMCRC and funded by the National Institute of Allergy and Infectious Diseases Radiation and Nuclear Countermeasures Program. It also explores the mechanisms of radiation-induced injuries, discusses existing medical countermeasures, and highlights emerging technologies and potential future directions for radiobiology researchers. This review aims to enhance our understanding of current medical countermeasures against radiation and contribute to the future development of more efficient and innovative approaches to mitigate and treat radiation-induced damage.

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医疗对抗辐射联盟中心：过去、现在和未来。

辐射医疗对策中心联盟（CMCRC）为随后的放射生物学科学提供了坚实的研究基础。然而，20年后，CMCRC将继续开展放射生物学利基领域的准备研究和先进产品开发，其中许多研究都是由CMCRC发起的。本文综述了由美国国家过敏和传染病研究所辐射和核对策项目资助的CMCRC开展的针对辐射损伤的医疗对策的过去和现在的策略和进展。它还探讨了辐射损伤的机制，讨论了现有的医疗对策，并为放射生物学研究人员强调了新兴技术和潜在的未来方向。这篇综述旨在提高我们对目前针对辐射的医疗对策的理解，并有助于未来开发更有效和创新的方法来减轻和治疗辐射引起的损伤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiation research 医学-核医学

CiteScore

5.10

自引率

8.80%

发文量

179

审稿时长

1 months

期刊介绍： Radiation Research publishes original articles dealing with radiation effects and related subjects in the areas of physics, chemistry, biology and medicine, including epidemiology and translational research. The term radiation is used in its broadest sense and includes specifically ionizing radiation and ultraviolet, visible and infrared light as well as microwaves, ultrasound and heat. Effects may be physical, chemical or biological. Related subjects include (but are not limited to) dosimetry methods and instrumentation, isotope techniques and studies with chemical agents contributing to the understanding of radiation effects.