Comparison of Biliary Drainage Techniques for MBO: A Meta-Analysis.

IF 1.7 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Pancreas Pub Date : 2025-06-25 DOI:10.1097/MPA.0000000000002504

Feng Qiu, Tianchi Yang, Wei Han

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引用次数: 0

Abstract

Background: Malignant biliary obstruction (MBO) impacts patient health and quality of life. Biliary drainage techniques, including percutaneous transhepatic biliary drainage (PTBD) and endoscopic biliary drainage (EBD), are commonly used, yet their relative advantages remain unclear.

Objective: To compare the effectiveness and complications of EBD and PTBD in treating MBO.

Methods: A systematic literature search in databases such as PubMed and EMBASE identified case-control trials comparing EBD and PTBD from January 2010 to the present. Five studies comprising 721 participants were analyzed. Outcome measures included technical success rate, incidence of complications, post-drainage pancreatitis, bleeding, major complications, hospital stay duration, and implant metastasis rates. Statistical analysis was conducted using RevMan 5.3 software.

Results: There was no significant difference between the two groups regarding major complications, bleeding incidents, hospital stay, or implantation metastasis rates. However, PTBD showed a significantly lower incidence of complications and post-drainage pancreatitis compared to EBD.

Conclusion: PTBD may offer advantages over EBD in managing MBO, including fewer complications and reduced incidence of pancreatitis, suggesting PTBD as a potentially safer and more effective treatment option. Nonetheless, further large-scale, high-quality studies are needed to validate these findings.

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胆道引流技术治疗MBO的比较：meta分析。

背景：恶性胆道梗阻（MBO）影响患者的健康和生活质量。胆道引流技术，包括经皮经肝胆道引流（PTBD）和内镜胆道引流（EBD），是常用的胆道引流技术，但它们的相对优势尚不清楚。目的：比较EBD与PTBD治疗MBO的疗效及并发症。方法：对PubMed和EMBASE等数据库进行系统文献检索，确定2010年1月至今比较EBD和PTBD的病例对照试验。包括721名参与者的5项研究进行了分析。结果测量包括技术成功率、并发症发生率、引流后胰腺炎、出血、主要并发症、住院时间和植入物转移率。采用RevMan 5.3软件进行统计分析。结果：两组患者在主要并发症、出血事件、住院时间和移植转移率方面无显著差异。然而，与EBD相比，PTBD的并发症和引流后胰腺炎的发生率明显降低。结论：PTBD在治疗MBO方面可能比EBD更有优势，包括更少的并发症和更低的胰腺炎发生率，这表明PTBD可能是一种更安全、更有效的治疗选择。然而，需要进一步大规模、高质量的研究来验证这些发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pancreas 医学-胃肠肝病学

CiteScore

4.70

自引率

3.40%

发文量

289

审稿时长

1 months

期刊介绍： Pancreas provides a central forum for communication of original works involving both basic and clinical research on the exocrine and endocrine pancreas and their interrelationships and consequences in disease states. This multidisciplinary, international journal covers the whole spectrum of basic sciences, etiology, prevention, pathophysiology, diagnosis, and surgical and medical management of pancreatic diseases, including cancer.