Incidence and risk factors for recurrence of incisional hernia repair after liver transplantation: a retrospective cohort study.

IF 2.4 2区医学 Q1 SURGERY

Hernia Pub Date : 2025-06-27 DOI:10.1007/s10029-025-03400-0

Edouard Wasielewski, Thierry Pecot, Estelle Le Pabic, Mohamed Lakehal, Astrid Herrero, Fabien Robin, Karim Boudjema, Laurent Sulpice

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引用次数: 0

Abstract

Purpose: The objective of this study was to evaluate the incidence and identify risk factors associated with the recurrence of incisional hernia (IH) following initial parietal repair in patients who had undergone liver transplantation. Liver transplantation (LT) is a complex procedure associated with numerous complications, particularly those affecting the abdominal wall, with incisional hernia (IH) being the most significant. To date, the risk factors contributing to IH recurrence in this population have not been systematically assessed.

Methods: This retrospective, single-center study included all patients who underwent liver transplantation at Rennes University Hospital between January 1, 2012, and December 31, 2018. The list of eligible patients was provided by the French Biomedicine Agency.

Results: A total of 803 liver transplant recipients were included. Among them, 282 patients (35.1%) developed an incisional hernia (IH) after a median follow-up of 75.87 months [54.7-97.2]. Of these, 50 patients (35.4%) experienced IH recurrence at a median interval of 8.8 months [5.2-34.2] following primary repair. Identified risk factors for recurrence included: length of hospital stay after the initial repair (HR: 1.09 [1.09-1.13], P = < 0.0001), type of repair (suture versus prosthetic) (HR: 2.48 [1.25-4.9], P = 0.009). Visceral obesity is considered a high-risk factor (HR: 2.21 [0.98-4.95], P = 0.055), although the association no longer reached the conventional threshold for statistical significance."

Conclusion: To the best of our knowledge, this is the first study to assess body composition as a risk factor for incisional hernia recurrence in the liver transplant population. These findings highlight the importance of considering visceral obesity as a significant predictor of recurrence.

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肝移植术后切口疝修补术后复发的发生率及危险因素：一项回顾性队列研究。

目的：本研究的目的是评估肝移植患者初始顶骨修复后切口疝（IH）复发的发生率和识别相关危险因素。肝移植（LT）是一项复杂的手术，有许多并发症，特别是影响腹壁的并发症，其中切口疝（IH）最为显著。迄今为止，在这一人群中导致IH复发的危险因素尚未得到系统评估。方法：这项回顾性的单中心研究纳入了2012年1月1日至2018年12月31日期间在雷恩大学医院接受肝移植的所有患者。符合条件的患者名单由法国生物医药局提供。结果：共纳入肝移植受者803例。其中282例（35.1%）患者在中位随访75.87个月后发生切口疝（IH）[54.7-97.2]。其中，50名患者（35.4%）在初次修复后的中位间隔8.8个月（5.2-34.2个月）出现IH复发。初步修复后住院时间（HR: 1.09 [1.09-1.13]）， P =结论：据我们所知，这是第一个评估身体成分作为肝移植人群切口疝复发危险因素的研究。这些发现强调了将内脏肥胖作为复发的重要预测因素的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hernia SURGERY-

CiteScore

4.90

自引率

26.10%

发文量

171

审稿时长

4-8 weeks

期刊介绍： Hernia was founded in 1997 by Jean P. Chevrel with the purpose of promoting clinical studies and basic research as they apply to groin hernias and the abdominal wall . Since that time, a true revolution in the field of hernia studies has transformed the field from a ”simple” disease to one that is very specialized. While the majority of surgeries for primary inguinal and abdominal wall hernia are performed in hospitals worldwide, complex situations such as multi recurrences, complications, abdominal wall reconstructions and others are being studied and treated in specialist centers. As a result, major institutions and societies are creating specific parameters and criteria to better address the complexities of hernia surgery. Hernia is a journal written by surgeons who have made abdominal wall surgery their specific field of interest, but we will consider publishing content from any surgeon who wishes to improve the science of this field. The Journal aims to ensure that hernia surgery is safer and easier for surgeons as well as patients, and provides a forum to all surgeons in the exchange of new ideas, results, and important research that is the basis of professional activity.