Modulating Thermal Stability and Flexibility in Chitosan Films with Neutral Polyol-Boric Acid Complexes

IF 5.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biomacromolecules Pub Date : 2025-07-14 DOI:10.1021/acs.biomac.5c00177

Olivia E. Coer, Brandy L. Davidson, Brycelyn M. Boardman, Gretchen M. Peters

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Abstract

The incorporation of boron into bioplastics offers the potential for diverse applications, with the structure–property relationship between polymer chains and boron species being the key for design. Here, we report the ability to modulate the flexibility and thermal stability of chitosan materials by varying the concentrations of erythritol and the molar equivalents of boric acid. Erythritol and boric acid form neutral complexes that alter the hydrogen-bonding face of erythritol while maintaining free diol units. 1D and 2D NMR experiments indicate preferential formation of the 1,3-isomer (85%) with minor amounts of 1,2- and 2,3-isomers. Structural, thermal, mechanical, and morphological characterization was performed using ATR-FTIR, TGA and DSC, DMA, and SEM, respectively. Molecular-level interactions of the complexes and d-glucosamine, the repeat unit of chitosan, showed increased aggregation and hydrogen-bonding interactions of the free diol units with the NH of d-glucosamine, supporting the trends in flexibility observed in the polymer system.

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查看原文本刊更多论文

中性多元醇-硼酸配合物对壳聚糖膜热稳定性和柔韧性的调节。

将硼加入到生物塑料中提供了多种应用的潜力，聚合物链和硼物种之间的结构-性能关系是设计的关键。在这里，我们报告了通过改变赤藓糖醇的浓度和硼酸的摩尔当量来调节壳聚糖材料的柔韧性和热稳定性的能力。赤藓糖醇和硼酸形成中性络合物，改变赤藓糖醇的氢键面，同时保持游离的二醇单位。一维和二维核磁共振实验表明，1,3-异构体（85%）优先形成，少量的1,2-和2,3-异构体。利用ATR-FTIR、TGA、DSC、DMA和SEM分别进行了结构、热、力学和形态表征。配合物与壳聚糖重复单元d-氨基葡萄糖的分子水平相互作用表明，游离二醇单元与d-氨基葡萄糖的NH之间的聚集和氢键相互作用增加，支持聚合物体系中观察到的柔韧性趋势。

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来源期刊

Biomacromolecules 化学-高分子科学

CiteScore

10.60

自引率

4.80%

发文量

417

审稿时长

1.6 months

期刊介绍： Biomacromolecules is a leading forum for the dissemination of cutting-edge research at the interface of polymer science and biology. Submissions to Biomacromolecules should contain strong elements of innovation in terms of macromolecular design, synthesis and characterization, or in the application of polymer materials to biology and medicine. Topics covered by Biomacromolecules include, but are not exclusively limited to: sustainable polymers, polymers based on natural and renewable resources, degradable polymers, polymer conjugates, polymeric drugs, polymers in biocatalysis, biomacromolecular assembly, biomimetic polymers, polymer-biomineral hybrids, biomimetic-polymer processing, polymer recycling, bioactive polymer surfaces, original polymer design for biomedical applications such as immunotherapy, drug delivery, gene delivery, antimicrobial applications, diagnostic imaging and biosensing, polymers in tissue engineering and regenerative medicine, polymeric scaffolds and hydrogels for cell culture and delivery.