Agenda for COVID-19 and long COVID research priorities in Brazil: results of wide consultation and Delphi consensus, 2022-2023.

Natália Silva Alves, Everton Nunes da Silva, Gabriela Bardelini Tavares Melo, Micaela Alexandra Silva Paulino, Antonia Angulo-Tuesta
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Abstract

Objective: To propose an agenda of COVID-19 and long COVID research priorities, in order to guide government and research funding agencies to optimize health science, technology and innovation resources in Brazil.

Methods: This is a qualitative study, carried out in two stages, between April 2022 and March 2023. In the first stage, a broad consultation was carried out to identify research priorities according to the axes of the COVID-19 Evidence Network to support Decision-making initiative, with 71 participants including researchers, health service managers, health science and technology managers, health professionals and health service users. In the second stage, a consensus was reached on the priorities proposed in the previous stage, using the Delphi method, with a panel of 20 experts on COVID-19 in the first round and 18 in the second round.

Results: In the broad consultation, 186 priority lines of research on COVID-19 were received and consolidated into 161 research lines. Of these, 139 achieved consensus in the first round of the Delphi method, and a further 40 lines were received and included in the second round for consensus. The proposed agenda has 179 research lines on COVID-19. The predominant themes were evaluation, COVID-19 impact and sequelae, long COVID-19, mental illnesses and immunosuppression. The child population was of greatest interest.

Conclusions: This study demonstrated high levels of agreement among participants on COVID-19 and long COVID research priorities in Brazil.

巴西COVID-19议程和COVID-19长期研究重点:2022-2023年广泛咨询和德尔菲共识的结果
目的:提出新冠肺炎议程和新冠肺炎长期研究重点,以指导巴西政府和科研资助机构优化卫生科技和创新资源。方法:本研究分两个阶段进行,时间为2022年4月至2023年3月。在第一阶段,开展了广泛磋商,根据COVID-19证据网络支持决策倡议的轴线确定研究重点,共有71名参与者,包括研究人员、卫生服务管理人员、卫生科技管理人员、卫生专业人员和卫生服务用户。第二阶段,采用德尔菲法,由20名专家组成第一轮专家组,18名专家组成第二轮专家组,就前一阶段提出的优先事项达成共识。结果:在广泛会诊中,共收到186个COVID-19重点研究方向,并整合为161个研究方向。其中,139条在第一轮德尔菲法中达成共识,另有40条被收到并纳入第二轮共识。拟议议程包括179个新冠肺炎研究项目。主要主题为评估、COVID-19的影响和后遗症、长期COVID-19、精神疾病和免疫抑制。儿童人口是最令人感兴趣的。结论:本研究表明,参与者对巴西的COVID-19和长期COVID研究重点具有高度一致性。
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