Beta-Tricalcium Phosphate (β-TCP) for Customized Bone Regeneration (CBR) in the Aesthetic Area of the Maxillary Anterior Alveolar Ridge.

Silvio Valdec, Fabienne A Bosshard, Andrea Patrizi, Nadja Naenni, Adib Al-Haj Husain
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Abstract

Purpose: Beta-tricalcium phosphate (β-TCP), a ceramic material renowned for its excellent biocompatibility, is widely used in oral tissue regeneration owing to its superior osteoconductive properties. This case report presents the surgical and prosthodontic management, along with a two-year clinical and radiological follow-up, of a patient-specific β TCP scaffold designed using computer-aided design and manufacturing (CAD/CAM) for the augmentation of a complex maxillary anterior alveolar ridge defect.

Material and methods: A 37-year-old male presented with a mispositioned implant in the maxillary anterior region, initially placed during adolescence. Ongoing alveolar ridge growth resulted in increased infraposition, exposed implant surface, and aesthetic concerns, requiring repeated prostheti corrections. Removal of the implant, followed by treatment using a patient-specific β-TCP scaffold, was performed to address both functional and aesthetic deficiencies. The scaffold was designed by means of CAD/CAM, providing a tailored solution for bone augmentation. Since the final restoration was planned without an implant-based rehabilitation, a resorbable magnesium screw was chosen as the fixation element to minimize the need for reintervention. Despite a buccal dehiscence that necessitated additional soft tissue grafting, the first year demonstrated excellent integration and successful prosthetic restoration. The two-year follow up still demonstrated successful clinical and aesthetic outcomes. However, radiological findings revealed ambiguous resorption patterns in the scaffold area, prompting concerns about potential complications.

Conclusions: This case highlights the benefits of using CAD/CAM-based β-TCP scaffolds for complex alveolar ridge augmentation, offering enhanced predictability and reduced perioperative technical challenges. Despite the complication of soft tissue dehiscence, the long-term clinical outcome was favorable. Further clinical research is necessary to assess the long-term effectiveness and possible limitations of β-TCP scaffolds in regenerative and reconstructive dentistry, particularly regarding resorption patterns and soft tissue integration. Close clinical monitoring is recommended to ensure optimal healing and prevent any adverse effects on the treatment outcome.

β-磷酸三钙(β-TCP)用于上颌前牙槽嵴美观区定制骨再生(CBR)。
目的:β-磷酸三钙(β-TCP)是一种以其优异的生物相容性而闻名的陶瓷材料,由于其优异的骨传导性而被广泛应用于口腔组织再生。本病例报告介绍了使用计算机辅助设计和制造(CAD/CAM)设计的患者特异性β TCP支架的手术和修复管理,以及两年的临床和放射学随访,用于增加复杂的上颌前牙槽嵴缺损。材料和方法:一名37岁男性,在上颌前区首次放置种植体时位置错误。持续的牙槽嵴生长导致假体移位增加、种植体表面暴露和美观问题,需要重复修复。移除植入物,然后使用患者特异性β-TCP支架进行治疗,以解决功能和美学缺陷。通过CAD/CAM对支架进行设计,为骨增强提供量身定制的解决方案。由于最终的修复计划没有植体康复,因此选择可吸收镁螺钉作为固定元件,以尽量减少再干预的需要。尽管颊裂需要额外的软组织移植,但第一年表现出良好的整合和成功的假体修复。两年的随访仍然显示了成功的临床和美学结果。然而,放射学结果显示支架区域的吸收模式不明确,引起了对潜在并发症的关注。结论:本病例强调了使用基于CAD/ cam的β-TCP支架进行复杂牙槽嵴增加的好处,提供了更高的可预测性和减少围手术期技术挑战。尽管有软组织破裂的并发症,但长期临床结果良好。需要进一步的临床研究来评估β-TCP支架在再生和重建牙科中的长期有效性和可能的局限性,特别是在吸收模式和软组织整合方面。建议密切的临床监测,以确保最佳的愈合和防止任何不良影响的治疗结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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