Identification and Management of Late toxicities after Radiotherapy for Vulvar Cancer.

IF 3.4 3区医学 Q2 ONCOLOGY

Practical Radiation Oncology Pub Date : 2025-06-23 DOI:10.1016/j.prro.2025.05.010

Cristina DeCesaris, Sabrina Bedell, David Gaffney, Gita Suneja, Lindsay Burt, Jeffrey Brower

引用次数: 0

Abstract

Vulvar cancer is a rare malignancy, with an estimated 6.900 cases diagnosed in 2024, though incidence has been rising in recent years¹. Radiation plays a critical role in definitive and adjuvant management, however late toxicities including pelvic insufficiency fractures (PIFs), anal/fecal incontinence, sexual dysfunction, cutaneous and sub-cutaneous fibrosis, and lymphedema may significantly impact quality of life in long-term survivors. This article will describe the most commonly encountered late radiation-induced toxicities seen in the management of vulvar cancers and provide practical guidance regarding work-up, and evidence-based management.

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外阴癌放疗后晚期毒性的识别与处理。

外阴癌是一种罕见的恶性肿瘤，据估计，2024年确诊病例为6900例，尽管近年来发病率一直在上升。放疗在最终和辅助治疗中起着关键作用，然而晚期毒性包括骨盆功能不全骨折（pif）、肛门/粪便失禁、性功能障碍、皮肤和皮下纤维化以及淋巴水肿可能会显著影响长期幸存者的生活质量。本文将描述在外阴癌治疗中最常见的晚期辐射引起的毒性，并提供有关检查和循证管理的实用指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Practical Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

6.10%

发文量

177

审稿时长

34 days

期刊介绍： The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes: Original articles focusing on patient safety, quality measurement, or quality improvement initiatives Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues ASTRO guidelines, position papers, and consensus statements Essays that highlight enriching personal experiences in caring for cancer patients and their families.