Effect of Early and Progressive Rehabilitation Protocol on Fatigue, Functional Outcome, and Kinesiophobia in Patients on Non-invasive Ventilation: A Randomized Controlled Trial.

IF 1.5 Q3 CRITICAL CARE MEDICINE

Indian Journal of Critical Care Medicine Pub Date : 2025-06-01 Epub Date: 2025-06-05 DOI:10.5005/jp-journals-10071-24992

Apurva C Vaidya, Vaibhav M Kapre, Santosh P Dobhal, Manish P Shukla, Abhishek S Mishra, Vibhuti Tiwari

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Abstract

Background and aims: Noninvasive ventilation (NIV) is being used increasingly in patients with respiratory conditions. The detrimental effects of intensive care unit (ICU) stay are well known and have to be minimized, and hence, a patient-centric, early, and progressive rehabilitation protocol is required. The present study aimed to evaluate the effect of early and progressive rehabilitation protocol on fatigue, functional outcome, and kinesiophobia, in patients on noninvasive mechanical ventilator.

Patients and methods: Patients of both genders admitted to the ICU and with assistance of NIV, due to primary respiratory condition, were included in the study. A total of 74 patients were randomized and allocated in both control and experimental groups. Control group was given conventional physiotherapy, while the experimental group was given early and progressive rehabilitation protocol.

Results: Early and progressive mobilization protocol showed a statistically significant improvement in fatigue levels, with p < 0.001 in between groups. The functional outcome PERME ICU mobility scale showed improvements in both groups (p < 0.001).

Conclusion: Early and patient-centric progressive rehabilitation protocol is safe and shown to improve the fatigue and mobility, and hence can be prescribed in patients with NIV assistance.

How to cite this article: Vaidya AC, Kapre VM, Dobhal SP, Shukla MP, Mishra AS, Tiwari V. Effect of Early and Progressive Rehabilitation Protocol on Fatigue, Functional Outcome, and Kinesiophobia in Patients on Non-invasive Ventilation: A Randomized Controlled Trial. Indian J Crit Care Med 2025;29(6):510-515.

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早期和渐进式康复方案对无创通气患者疲劳、功能结局和运动恐惧症的影响：一项随机对照试验。

背景和目的：无创通气（NIV）在呼吸系统疾病患者中的应用越来越多。重症监护病房（ICU）的有害影响是众所周知的，必须尽量减少，因此，需要一个以患者为中心的、早期的、渐进的康复方案。本研究旨在评估早期和渐进式康复方案对无创机械呼吸机患者的疲劳、功能结局和运动恐惧症的影响。患者和方法：本研究纳入了因原发性呼吸疾病而入住ICU并使用NIV辅助的男女患者。74例患者随机分为对照组和实验组。对照组给予常规物理治疗，实验组给予早期渐进式康复方案。结果：早期和渐进式活动方案对疲劳水平的改善有统计学意义，组间p < 0.001。功能结局PERME ICU活动能力评分两组均有改善（p < 0.001）。结论：早期和以患者为中心的渐进式康复方案是安全的，可以改善疲劳和活动能力，因此可以在有NIV辅助的患者中使用。Vaidya AC, Kapre VM, Dobhal SP, Shukla MP, Mishra AS, Tiwari V.早期和渐进式康复方案对无创通气患者疲劳、功能结局和运动恐惧症的影响：一项随机对照试验。中华检验医学杂志，2015;29(6):510-515。

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来源期刊

Indian Journal of Critical Care Medicine CRITICAL CARE MEDICINE-

CiteScore

3.50

自引率

10.00%

发文量

299

期刊介绍： Indian Journal of Critical Care Medicine (ISSN 0972-5229) is specialty periodical published under the auspices of Indian Society of Critical Care Medicine. Journal encourages research, education and dissemination of knowledge in the fields of critical and emergency medicine.