Vaccination in patients with heart failure in practice.

IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
François Roubille, Nicolas Chapet, Camille Roubille, Marc Villacèque, Clément Delmas, Muriel Salvat, Frédéric Mouquet, Thibaud Damy, Jean-Michel Tartiere, Emmanuelle Berthelot, Peter Libby, Gianluigi Savarese, Paul Loubet, Nicolas Girerd
{"title":"Vaccination in patients with heart failure in practice.","authors":"François Roubille, Nicolas Chapet, Camille Roubille, Marc Villacèque, Clément Delmas, Muriel Salvat, Frédéric Mouquet, Thibaud Damy, Jean-Michel Tartiere, Emmanuelle Berthelot, Peter Libby, Gianluigi Savarese, Paul Loubet, Nicolas Girerd","doi":"10.1093/eurjpc/zwaf366","DOIUrl":null,"url":null,"abstract":"<p><p>This narrative review underscores the pivotal role of vaccination in mitigating respiratory infections and associated acute decompensations in heart failure (HF) patients. It highlights the necessity for heightened awareness and proactive engagement among healthcare providers to bridge vaccination gaps and enhance preventive care for HF patients. Respiratory pathogens, such as influenza, pneumococcus, SARS-CoV2, and Herpes zoster virus (VZV), instigate systemic inflammation and increase cardiovascular events, markedly elevating the risk of HF and strokes, especially in individuals with preexisting conditions. Respiratory infections further amplify the risk of thrombotic events in HF patients through mechanisms involving a heightened procoagulant status due to inflammation. Systemic inflammation often accompanies HF, contributing to its progression, complications, and acute episodes, particularly during respiratory infections. While promising therapeutic approaches are under development, the review aims to provide a comprehensive overview of the pathophysiology linking inflammation, infection, and HF. The review then explores current clinical knowledge on the protective effects of vaccines against respiratory diseases (influenza, pneumococcal infection, SARS-CoV2, RSV, and emerging pathogens) in HF patients, along with the key applicable guidelines. It also offers strategies to enhance vaccination coverage in HF patients, highlighting practical issues pertinent to daily clinical practice.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of preventive cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/eurjpc/zwaf366","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

This narrative review underscores the pivotal role of vaccination in mitigating respiratory infections and associated acute decompensations in heart failure (HF) patients. It highlights the necessity for heightened awareness and proactive engagement among healthcare providers to bridge vaccination gaps and enhance preventive care for HF patients. Respiratory pathogens, such as influenza, pneumococcus, SARS-CoV2, and Herpes zoster virus (VZV), instigate systemic inflammation and increase cardiovascular events, markedly elevating the risk of HF and strokes, especially in individuals with preexisting conditions. Respiratory infections further amplify the risk of thrombotic events in HF patients through mechanisms involving a heightened procoagulant status due to inflammation. Systemic inflammation often accompanies HF, contributing to its progression, complications, and acute episodes, particularly during respiratory infections. While promising therapeutic approaches are under development, the review aims to provide a comprehensive overview of the pathophysiology linking inflammation, infection, and HF. The review then explores current clinical knowledge on the protective effects of vaccines against respiratory diseases (influenza, pneumococcal infection, SARS-CoV2, RSV, and emerging pathogens) in HF patients, along with the key applicable guidelines. It also offers strategies to enhance vaccination coverage in HF patients, highlighting practical issues pertinent to daily clinical practice.

心力衰竭患者接种疫苗的实践。
这篇叙述性综述强调了疫苗接种在减轻心力衰竭(HF)患者呼吸道感染和相关急性代偿失调中的关键作用。它强调了提高卫生保健提供者的认识和积极参与的必要性,以弥合疫苗接种差距并加强对心力衰竭患者的预防性护理。呼吸道病原体,如流感、肺炎球菌、SARS-CoV2和带状疱疹病毒(VZV),会引发全身炎症并增加心血管事件,显著提高心衰和中风的风险,特别是在已有疾病的个体中。呼吸道感染通过炎症引起的促凝状态升高的机制进一步增加了HF患者血栓形成事件的风险。全身性炎症常伴发心衰,导致其进展、并发症和急性发作,特别是在呼吸道感染期间。虽然有希望的治疗方法正在开发中,但本文旨在全面概述炎症、感染和心衰之间的病理生理学联系。然后,综述探讨了目前关于疫苗对HF患者呼吸道疾病(流感、肺炎球菌感染、SARS-CoV2、RSV和新发病原体)保护作用的临床知识,以及关键的适用指南。它还提供了提高心hf患者疫苗接种覆盖率的策略,突出了与日常临床实践相关的实际问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
European journal of preventive cardiology
European journal of preventive cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
12.50
自引率
12.00%
发文量
601
审稿时长
3-8 weeks
期刊介绍: European Journal of Preventive Cardiology (EJPC) is an official journal of the European Society of Cardiology (ESC) and the European Association of Preventive Cardiology (EAPC). The journal covers a wide range of scientific, clinical, and public health disciplines related to cardiovascular disease prevention, risk factor management, cardiovascular rehabilitation, population science and public health, and exercise physiology. The categories covered by the journal include classical risk factors and treatment, lifestyle risk factors, non-modifiable cardiovascular risk factors, cardiovascular conditions, concomitant pathological conditions, sport cardiology, diagnostic tests, care settings, epidemiology, pharmacology and pharmacotherapy, machine learning, and artificial intelligence.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信