Cognitive Stimulation and Strength Training in Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial.

IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Juan Miguel Muñoz-Perete, María Del Mar Carcelén-Fraile, Yolanda Castellote-Caballero, María Del Carmen Carcelén-Fraile
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Abstract

Background/Objectives: The global increase in life expectancy has led to a higher prevalence of cognitive and physical decline in older adults, particularly in those with mild cognitive impairment (MCI). This study aimed to evaluate the effects of a combined cognitive stimulation and resistance training intervention on cognitive performance, physical function, and fall risk in older adults with MCI. Methods: A randomized controlled trial was conducted with 80 community-dwelling older adults diagnosed with MCI. Participants were randomly assigned to an experimental group (EG), which received a 12-week intervention consisting of cognitive stimulation and progressive strength training, or a control group (CG), which maintained their usual routine. Pre- and post-intervention assessments included measures of cognitive function, verbal fluency, attention, processing speed, executive function, gait, balance, fall risk, and lower- and upper-body strength. Results: The EG showed significant improvements compared with the CG in cognitive impairment, verbal fluency, processing speed, balance, gait, and risk of falls (all p < 0.05), with effect sizes ranging from moderate to large. Notably, strength gains were observed in both lower body and grip strength. Attention and executive function also improved in the EG, although with smaller effect sizes. No adverse events were reported. Conclusions: A combined intervention of cognitive stimulation and resistance training is effective in improving multiple domains of cognitive and physical function in older adults with MCI. These findings support the integration of multidomain interventions in clinical and community settings to promote autonomy, reduce fall risk, and delay cognitive and functional decline. Future studies should explore the long-term sustainability of these effects and the individual contribution of each intervention component.

老年轻度认知障碍患者的认知刺激和力量训练:一项随机对照试验。
背景/目的:全球预期寿命的增加导致老年人认知和身体衰退的患病率更高,特别是在轻度认知障碍(MCI)患者中。本研究旨在评估认知刺激和抗阻训练联合干预对老年轻度认知障碍患者认知表现、身体功能和跌倒风险的影响。方法:对80名诊断为轻度认知障碍的社区老年人进行随机对照试验。参与者被随机分配到实验组(EG),实验组接受为期12周的干预,包括认知刺激和渐进式力量训练,而对照组(CG)则保持常规。干预前和干预后的评估包括认知功能、语言流畅性、注意力、处理速度、执行功能、步态、平衡、跌倒风险以及下肢和上肢力量的测量。结果:与CG相比,EG在认知障碍、语言流畅性、处理速度、平衡、步态和跌倒风险方面均有显著改善(p < 0.05),效应量从中等到较大。值得注意的是,在下半身和握力方面都观察到力量的增加。EG的注意力和执行功能也有所改善,尽管效果较小。无不良事件报告。结论:认知刺激和抗阻训练的联合干预对老年轻度认知损伤患者多领域的认知和身体功能的改善是有效的。这些发现支持在临床和社区环境中整合多领域干预措施,以促进自主性,降低跌倒风险,并延缓认知和功能衰退。未来的研究应该探索这些影响的长期可持续性以及每个干预成分的个体贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diagnostics
Diagnostics Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
4.70
自引率
8.30%
发文量
2699
审稿时长
19.64 days
期刊介绍: Diagnostics (ISSN 2075-4418) is an international scholarly open access journal on medical diagnostics. It publishes original research articles, reviews, communications and short notes on the research and development of medical diagnostics. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodological details must be provided for research articles.
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