Corticospinal excitability is facilitated during coordinative action observation and motor imagery.

IF 2.9 2区医学 Q2 NEUROSCIENCES

Cerebral cortex Pub Date : 2025-06-04 DOI:10.1093/cercor/bhaf157

Ashika Chembila Valappil, Neža Grilc, Federico Castelli, Samantha Chye, David J Wright, Christopher J Tyler, Ryan Knight, Omar S Mian, Neale A Tillin, Adam M Bruton

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引用次数: 0

Abstract

Combined action observation and motor imagery (AOMI) facilitates corticospinal excitability (CSE). This study used single-pulse transcranial magnetic stimulation (TMS) to explore changes in CSE for coordinative AOMI, where the observed and imagined actions are related but not identical, for a single-leg sit-to-stand (SL-STS) movement. Twenty-one healthy adults completed two testing sessions including baseline (BL), action observation (AO), and motor imagery (MI) control conditions, and three experimental conditions where they observed a slow-paced SL-STS while simultaneously imagining a slow- (AOMIHICO), medium- (AOMIMOCO), or fast-paced (AOMILOCO) SL-STS. A TMS pulse was delivered to the right leg representation of the left primary motor cortex at three stimulation timepoints aligned with peak electromyography (EMG) activity of the knee extensor muscle group for the fast- (T1), medium- (T2), and slow-paced (T3) SL-STS during each condition. Motor evoked potential (MEP) amplitudes were recorded from the knee extensor muscle group as a marker of CSE for all stimulation timepoints and conditions. A main effect for experimental condition was reported for all stimulation timepoints. MEP amplitudes were significantly greater for AOMIHICO at T1 and T3, and AOMIMOCO and AOMILOCO at all stimulation timepoints, when compared with control conditions. This study provides neurophysiological evidence supporting the use of coordinative AOMI.

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皮质脊髓兴奋性在协调动作观察和运动想象过程中得到促进。

联合动作观察和运动想象（AOMI）促进皮质脊髓兴奋性（CSE）。本研究使用单脉冲经颅磁刺激（TMS）来探索协调AOMI的CSE变化，其中观察到的和想象的动作是相关的，但不相同，单腿坐立（SL-STS）运动。21名健康成人完成了包括基线（BL）、动作观察（AO）和运动想象（MI）控制条件在内的两个测试阶段，以及在观察慢节奏SL-STS的同时想象慢节奏（AOMIHICO）、中节奏（AOMIMOCO）或快节奏（AOMILOCO） SL-STS的三个实验条件。在三个刺激时间点，将TMS脉冲传递到右腿左侧初级运动皮层，这些时间点与快速（T1），中速（T2）和慢速（T3） SL-STS的膝关节伸肌群的肌电图（EMG）活动峰值一致。记录膝关节伸肌群的运动诱发电位（MEP）振幅，作为所有刺激时间点和条件下CSE的标志。实验条件对所有刺激时间点都有主要影响。与对照组相比，AOMIHICO组在T1和T3以及AOMIMOCO和AOMILOCO组在所有刺激时间点的MEP振幅均显著高于对照组。本研究为支持协调性AOMI的使用提供了神经生理学证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cerebral cortex 医学-神经科学

CiteScore

6.30

自引率

8.10%

发文量

510

审稿时长

2 months

期刊介绍： Cerebral Cortex publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus. Studies with clear relevance to the cerebral cortex, such as the thalamocortical relationship or cortico-subcortical interactions, are also included. The journal is multidisciplinary and covers the large variety of modern neurobiological and neuropsychological techniques, including anatomy, biochemistry, molecular neurobiology, electrophysiology, behavior, artificial intelligence, and theoretical modeling. In addition to research articles, special features such as brief reviews, book reviews, and commentaries are included.