Feline caudal vena cava-to-aorta ratio and left atrial-to-aortic root ratio increase in acute hypervolemia.

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

American journal of veterinary research Pub Date : 2025-06-25 DOI:10.2460/ajvr.25.04.0114

Adam Whitelock, Katherine Nash, Keely Sayer, Wendy Goodwin

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引用次数: 0

Abstract

Objective: To evaluate the caudal vena cava-to-aorta (CVC:Ao) ratio at the hepatorenal location and left atrial-to-aortic root (LA:Ao) ratio as ultrasonographic indicators of acute hypervolemia in cats.

Methods: 10 healthy adult cats underwent general anesthesia with sevoflurane and were experimentally administered incremental volumes of lactated Ringer solution to achieve cumulative blood volume increases of 50%, 100%, 150%, and 200%. Point-of-care ultrasound measurements of the CVC:Ao and LA:Ao ratios were obtained at baseline, following each fluid bolus, and 15 minutes after the final infusion. All measurements were performed in triplicate.

Results: Both CVC:Ao and LA:Ao ratios demonstrated increases from baseline at all time points. Following the initial fluid bolus (50% blood volume), the mean CVC:Ao ratio increased by 47% (mean difference, -0.51; 95% CI, -0.74 to 0.28), and the LA:Ao ratio increased by 26% (mean difference, -0.33; 95% CI, -0.58 to 0.07) from baseline. During the redistribution phase (15 minutes following final infusion), the LA:Ao ratio decreased significantly compared to postinfusion values, while the CVC:Ao ratio did not. Intraobserver reliability was good to excellent for the LA:Ao ratio (intraclass correlation coefficient, 0.88; 95% CI, 0.82 to 0.92) and moderate to good for the CVC:Ao ratio (intraclass correlation coefficient, 0.79; 95% CI, 0.70 to 0.86).

Conclusions: The CVC:Ao and LA:Ao ratios increased during acute hypervolemia in cats. The ultrasonographic measurements demonstrated good to excellent intraobserver reliability. The decrease in the LA:Ao ratio during the redistribution phase supports previous findings regarding rapid crystalloid redistribution in cats.

Clinical relevance: The CVC:Ao and LA:Ao ratios may serve as useful indicators of volume status in feline patients; however, studies in conscious clinical patients are warranted to further validate these findings in cats.

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猫尾腔静脉与主动脉的比值和左心房与主动脉根的比值在急性高血容量时增加。

目的：探讨猫肝肾端尾腔静脉与主动脉（CVC:Ao）比值和左心房与主动脉根（LA:Ao）比值作为急性高血容量超声指标的价值。方法：对10只健康成年猫进行七氟醚全身麻醉，并实验性地给予增量乳酸林格液，使累积血容量增加50%、100%、150%和200%。在基线、每次输液后和最后一次输注后15分钟，获得CVC:Ao和LA:Ao比值的即时超声测量。所有测量均为三份。结果：CVC:Ao和LA:Ao比值在所有时间点均较基线升高。初始补液（50%血容量）后，CVC:Ao比平均增加47%(平均差值为-0.51；95% CI, -0.74 ~ 0.28)， LA:Ao比值增加26%(平均差值，-0.33；95% CI, -0.58至0.07)。在再分配阶段（末次输注后15分钟），LA:Ao比值与输注后值相比显著下降，而CVC:Ao比值则没有。LA:Ao比值的观察者内信度为良好至优异(类内相关系数0.88；95% CI, 0.82 - 0.92)和中度至良好的CVC:Ao比值(类内相关系数，0.79；95% CI, 0.70 ~ 0.86)。结论：猫急性高血容量时CVC:Ao和LA:Ao比值升高。超声测量显示良好至优异的观察者内可靠性。在重新分配阶段，LA:Ao比值的下降支持了先前关于猫体内晶体快速重新分配的发现。临床相关性：CVC:Ao和LA:Ao比值可以作为猫患者体积状态的有用指标；然而，在有意识的临床患者中进行的研究有必要进一步验证猫的这些发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of veterinary research 农林科学-兽医学

CiteScore

1.70

自引率

10.00%

发文量

186

审稿时长

3 months

期刊介绍： The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.